The role of copper(II) in the aggregation of human amylin

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The role of copper(II) in the aggregation of human amylin

Amylin is the 37-residue peptide hormone produced by the islet β-cells in the pancreas and the formation of amylin aggregates is strongly associated with β-cells degeneration in type 2 diabetes, as demonstrated by more than 95% of patients exhibiting amylin amyloid upon autopsy. It is widely recogni...

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Bibliographic Details
Main Authors:	Sinopoli, Alessandro, Magrì, Antonio, Milardi, Danilo, Pappalardo, Matteo, Pucci, Pietro, Flagiello, Angela, Titman, Jeremy J., Nicoletti, Vincenzo G., Caruso, Giuseppe, Pappalardo, Giuseppe, Grasso, Giuseppe
Format:	Article
Published:	Royal Society of Chemistry 2014
Online Access:	https://eprints.nottingham.ac.uk/3323/

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