Enhanced latent inhibition in high schizotypy individuals

Latent inhibition refers to a retardation in learning about a stimulus that has been rendered familiar by non-reinforced preexposure, relative to a non-preexposed stimulus. Latent inhibition has been shown to be inversely correlated with schizotypy, and abnormal in people with schizophrenia, but the...

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Main Authors: Granger, Kiri T., Moran, Paula M., Buckley, Matthew G., Haselgrove, Mark
Format: Article
Published: 2016
Online Access:https://eprints.nottingham.ac.uk/33001/
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author Granger, Kiri T.
Moran, Paula M.
Buckley, Matthew G.
Haselgrove, Mark
author_facet Granger, Kiri T.
Moran, Paula M.
Buckley, Matthew G.
Haselgrove, Mark
author_sort Granger, Kiri T.
building Nottingham Research Data Repository
collection Online Access
description Latent inhibition refers to a retardation in learning about a stimulus that has been rendered familiar by non-reinforced preexposure, relative to a non-preexposed stimulus. Latent inhibition has been shown to be inversely correlated with schizotypy, and abnormal in people with schizophrenia, but these findings are inconsistent. One potential contributing factor to this inconsistency is that many tasks that purport to measure latent inhibition are confounded by alternative effects that also retard learning and co-vary with schizotypy (e.g. learned irrelevance and conditioned inhibition). Here, two within-participant experiments are reported that measure the effect of familiarity on learning without the confound of these alternative effects. Consistent with some of the clinical literature, a positive association was found between the rate of learning to the familiar, but not the novel, stimulus and the unusual-experiences dimension of schizotypy — implying abnormally persistent latent inhibition in high schizotypy individuals.
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spelling nottingham-330012020-05-04T17:34:21Z https://eprints.nottingham.ac.uk/33001/ Enhanced latent inhibition in high schizotypy individuals Granger, Kiri T. Moran, Paula M. Buckley, Matthew G. Haselgrove, Mark Latent inhibition refers to a retardation in learning about a stimulus that has been rendered familiar by non-reinforced preexposure, relative to a non-preexposed stimulus. Latent inhibition has been shown to be inversely correlated with schizotypy, and abnormal in people with schizophrenia, but these findings are inconsistent. One potential contributing factor to this inconsistency is that many tasks that purport to measure latent inhibition are confounded by alternative effects that also retard learning and co-vary with schizotypy (e.g. learned irrelevance and conditioned inhibition). Here, two within-participant experiments are reported that measure the effect of familiarity on learning without the confound of these alternative effects. Consistent with some of the clinical literature, a positive association was found between the rate of learning to the familiar, but not the novel, stimulus and the unusual-experiences dimension of schizotypy — implying abnormally persistent latent inhibition in high schizotypy individuals. 2016-03-01 Article PeerReviewed Granger, Kiri T., Moran, Paula M., Buckley, Matthew G. and Haselgrove, Mark (2016) Enhanced latent inhibition in high schizotypy individuals. Personality and Individual Differences, 91 . pp. 31-39. ISSN 01918869 http://dx.doi.org/10.1016/j.paid.2015.11.040 doi:10.1016/j.paid.2015.11.040 doi:10.1016/j.paid.2015.11.040
spellingShingle Granger, Kiri T.
Moran, Paula M.
Buckley, Matthew G.
Haselgrove, Mark
Enhanced latent inhibition in high schizotypy individuals
title Enhanced latent inhibition in high schizotypy individuals
title_full Enhanced latent inhibition in high schizotypy individuals
title_fullStr Enhanced latent inhibition in high schizotypy individuals
title_full_unstemmed Enhanced latent inhibition in high schizotypy individuals
title_short Enhanced latent inhibition in high schizotypy individuals
title_sort enhanced latent inhibition in high schizotypy individuals
url https://eprints.nottingham.ac.uk/33001/
https://eprints.nottingham.ac.uk/33001/
https://eprints.nottingham.ac.uk/33001/