Efficient preparation of TMSCCl2Br and its use in dichlorocyclopropanation of electron deficient alkenes

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Efficient preparation of TMSCCl2Br and its use in dichlorocyclopropanation of electron deficient alkenes

The reaction of excess TMSCl and LiCCl2Br at low temperature is a technically simple high yield route to TMSCCl2Br. The latter is a stable source of the dichlorobromomethide carbanion, which undergoes 1,4-addition with cyclic nitroalkenes and (E)-fumarates leading to dichlorocyclopropanes after brom...

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Bibliographic Details
Main Authors:	Lee, Darren S., Durán-Peña, Maria Jesus, Burroughs, Laurence, Woodward, Simon
Format:	Article
Published:	Wiley-VCH Verlag 2016
Subjects:	Dichlorocyclopropane Michael Addition Cyclopropanation Conjugate Addition Cyclopropane
Online Access:	https://eprints.nottingham.ac.uk/32995/

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