Elevated levels of plasma homocysteine, deficiencies in dietary folic acid and uracil–DNA glycosylase impair learning in a mouse model of vascular cognitive impairment

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Elevated levels of plasma homocysteine, deficiencies in dietary folic acid and uracil–DNA glycosylase impair learning in a mouse model of vascular cognitive impairment

Dietary deficiencies in folic acid result in elevated levels of plasma homocysteine, which has been associated with the development of dementia and other neurodegenerative disorders. Previously, we have shown that elevated levels of plasma homocysteine in mice deficient for a DNA repair enzyme, urac...

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Bibliographic Details
Main Authors:	Jadavji, Nafisa M., Farr, Tracy D., Lips, Janet, Khalil, Ahmed A., Boehm-Sturm, Philipp, Foddis, Marco, Harms, Christoph, Füchtemeier, Martina, Dirnagl, Ulrich
Format:	Article
Published:	Elsevier 2015
Subjects:	Chronic hypoperfusion; Folate; Homocysteine; Matrix metalloproteinases-9; Morris watermaze; Uracil-DNA glycosylase
Online Access:	https://eprints.nottingham.ac.uk/32983/

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