Helicobacter pylori vacA transcription is genetically-determined and stratifies the level of human gastric inflammation and atrophy

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Helicobacter pylori vacA transcription is genetically-determined and stratifies the level of human gastric inflammation and atrophy

Aims Helicobacter pylori infection is the major cause of peptic ulceration and gastric cancer, and an important virulence determinant is its vacuolating cytotoxin, vacA. Previously, we have described allelic variation in vacA which determines toxin activity and disease risk. We now aimed to quan...

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Bibliographic Details
Main Authors:	Sinnett, Charlotte G., Letley, Darren P., Narayan, Geetha L., Patel, Sapna Rohitbhai, Hussein, Nawfal Rasheed, Zaitoun, Abed M., Robinson, Karen, Atherton, John C.
Format:	Article
Published:	BMJ Publishing Group Ltd 2016
Subjects:	Bacterial toxin; pathogenesis; Helicobacter pylori; vacuolating cytotoxin; VacA
Online Access:	https://eprints.nottingham.ac.uk/32869/

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