The role of acid-base imbalance in statin-induced myotoxicity

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The role of acid-base imbalance in statin-induced myotoxicity

Disturbances in acid-base balance, such as acidosis and alkalosis, have potential to alter the pharmacological and toxicological outcomes of statin therapy. Statins are commonly prescribed for elderly patients who have multiple co-morbidities such as diabetes mellitus, cardiovascular and renal disea...

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Bibliographic Details
Main Authors:	Taha, Dhiaa A., de Moor, Cornelia H., Barrett, David A., Lee, Jong Bong, Gandhi, Raj D., Hoo, Chei Wei, Gershkovich, Pavel
Format:	Article
Published:	Elsevier 2016
Subjects:	Acidosis; Alkalosis; Cellular uptake; Inter-conversion; Myotoxicity; Pravastatin; Simvastatin
Online Access:	https://eprints.nottingham.ac.uk/32864/

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