FK866 reduces axon pathology in in vitro and in vivo models of Huntington’s disease and Alzheimer’s disease and attenuates behavioral abnormalities

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FK866 reduces axon pathology in in vitro and in vivo models of Huntington’s disease and Alzheimer’s disease and attenuates behavioral abnormalities

Among its various biological functions, NAD metabolism regulates axon degeneration, which is an early and often causative event in a variety of neurodegenerative diseases including Huntington’s disease (HD) and Alzheimer’s disease (AD). Our research group previously found that reducing the levels o...

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Bibliographic Details
Main Author:	Othman, Othman Ahmad
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	Alzheimer’s disease Huntington’s disease FK866 NAMPT NMN
Online Access:	https://eprints.nottingham.ac.uk/32669/

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