The impact of azithromycin therapy on the airway microbiota in asthma

QR Code

The impact of azithromycin therapy on the airway microbiota in asthma

There is interest in the use of macrolide antibiotics in asthma. Macrolides have been shown to improve airway hyperresponsiveness (AHR) and measures of airway inflammation.The degree of AHR may relate to the microbiota present in the airways, with a recent study reporting that patients with asthma w...

Full description

Bibliographic Details
Main Authors:	Slater, Mariel, Rivett, Damian W., Williams, Lisa, Martin, Matthew, Harrison, Timothy W., Sayers, Ian, Bruce, Kenneth D., Shaw, Dominick E.
Format:	Article
Published:	BMJ Publishing Group 2014
Online Access:	https://eprints.nottingham.ac.uk/32641/

Similar Items

The differential effects of azithromycin on the airway epithelium in vitro and in vivo
by: Slater, Mariel, et al.
Published: (2016)

Predicting response to Azithromycin therapy in asthma
by: Slater, Mariel
Published: (2015)

Step 4: stick or twist? A review of asthma therapy
by: Slater, Mariel G., et al.
Published: (2016)

Azithromycin for Acute Exacerbations of Asthma: the AZALEA randomized clinical trial
by: Johnson, Sebastian L., et al.
Published: (2016)

Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma
by: Rogers, Natasha K., et al.
Published: (2014)

MMP-1 activation contributes to airway smooth muscle growth and asthma severity
by: Naveed, Shams-un-nisa, et al.
Published: (2017)

Inhaled corticosteroids and the risk of pneumonia in people with asthma
by: McKeever, Tricia M., et al.
Published: (2013)

Azithromycin Mitigates Human Rhinovirus Impact On Epithelial Junctional Proteins And Barrier Function In Airway Epithelium
by: Looi, K., et al.
Published: (2017)

Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction
by: Tubby, Carolyn, et al.
Published: (2016)

Long-Term Azithromycin Reduces Haemophilus influenzae and Increases Antibiotic Resistance in Severe Asthma
by: Taylor, S.L., et al.
Published: (2019)

Azithromycin reduces airway inflammation induced by human rhinovirus in lung allograft recipients
by: Ling, K.M., et al.
Published: (2019)

Epithelial Injury and Dysregulated Repair in Small and Large Airways of Lung Transplant Patients is Ameliorated by Azithromycin
by: Kicic, Anthony, et al.
Published: (2014)

Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma
by: Ierodiakonou, Despo, et al.
Published: (2016)

Untargeted metabolic profiling of saliva by liquid chromatography-mass spectrometry for the identification of potential diagnostic biomarkers of asthma
by: Malkar, Aditya, et al.
Published: (2016)

DYSREGULATED REPAIR AND EPITHELIAL INJURY IN SMALL AND LARGE AIRWAYS OF LUNG TRANSPLANT PATIENTS IS AMELIORATED BY AZITHROMYCIN
by: Kicic, Anthony, et al.
Published: (2014)

The effects of azithromycin in treatment-resistant cough: a randomized, double-blind, placebo-controlled trial
by: Hodgson, David, et al.
Published: (2016)

A randomised controlled trial of small particle inhaled steroids in refractory eosinophilic asthma (SPIRA)
by: Hodgson, David, et al.
Published: (2015)

The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma
by: Ketelaar, M.E., et al.
Published: (2016)

Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identiﬁes a severe, nonatopic subset of patients
by: Portelli, Michael A., et al.
Published: (2016)

A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
by: Patel, Mitesh Dilipkumar Kantilal, et al.
Published: (2015)

Genetic basis for personalized medicine in asthma
by: Portelli, Michael A., et al.
Published: (2012)

Genome-wide association studies in asthma
by: Portelli, Michael A., et al.
Published: (2016)

Asthma and unified airways disease through epithelial cells
by: De Jong, E., et al.
Published: (2018)

Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children
by: Tulah, Asif S., et al.
Published: (2013)

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
by: Jevnikar, Zala, et al.
Published: (2018)

IDENTIFYING A NOVEL THERAPEUTIC STRATEGY FOR ASTHMA: TARGETING AIRWAY EPITHELIAL CELL RESTITUTION
by: Iosifidis, T., et al.
Published: (2017)

An investigation into the synergistic relationship between lactoferrin and azithromycin with particular reference to periodontopathic bacteria
by: Husain, Juzaily, et al.
Published: (2019)

The role of histone arginine methylation in gene expression of airway smooth muscle cells in asthma
by: Kaczmarek, K.A., et al.
Published: (2017)

Bradycardia and hypothermia complicating azithromycin treatment
by: Benn, K., et al.
Published: (2017)

The role of histone arginine methylation in gene expression of airway smooth muscle cells in asthma
by: Kaczmarek, K.A., et al.
Published: (2016)

Impaired airway epithelial cell responses from children with asthma to rhinoviral infection
by: Kicic, Anthony, et al.
Published: (2016)

Burden of disease and benefits of exercise in fixed airway obstruction asthma
by: Turner, Sian Elizabeth
Published: (2009)

Comparable reductions in hyperpnoea-induced bronchoconstriction and markers of airway inflammation after supplementation with 6·2 and 3·1 g/d of long-chain n-3 PUFA in adults with asthma
by: Williams, Neil C., et al.
Published: (2017)

Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma
by: Matthey, Michaela, et al.
Published: (2017)

Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma
by: Donovan, G.M., et al.
Published: (2020)

Exhaled nitric oxide and inhaled corticosteroid dose reduction in asthma: a cohort study
by: Wilson, Emma, et al.
Published: (2014)

Azithromycin Inhibits Mesenchymal Transition of Allograft Epithelium
by: Banerjee, B., et al.
Published: (2011)

Coagulation factors in the airways in moderate and severe asthma and the effect of inhaled steroids
by: Brims, Fraser, et al.
Published: (2009)

Azithromycin for treatment of bronchiolitis obliterans syndrome in adult lung transplant recipients
by: Safavi, Shahideh, et al.
Published: (2017)

Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma
by: Johnathan, Malagobadan, et al.
Published: (2021)