Discovery of novel alphacoronaviruses in European rodents and shrews
Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex araneus and Myodes glareolus. These, together with t...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI
2016
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| Online Access: | https://eprints.nottingham.ac.uk/32400/ |
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| author | Tsoleridis, Theocharis Onianwa, Okechukwu Horncastle, Emma Dayman, Emma Zhu, Miaoran Danjittrong, Taechasit Wachtl, Marta Behnke, Jerzy M. Chapman, Sarah Strong, Victoria Dodds, Phillipa Tarlinton, Rachael E. Ball, Jonathan K. McClure, Patrick |
| author_facet | Tsoleridis, Theocharis Onianwa, Okechukwu Horncastle, Emma Dayman, Emma Zhu, Miaoran Danjittrong, Taechasit Wachtl, Marta Behnke, Jerzy M. Chapman, Sarah Strong, Victoria Dodds, Phillipa Tarlinton, Rachael E. Ball, Jonathan K. McClure, Patrick |
| author_sort | Tsoleridis, Theocharis |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex araneus and Myodes glareolus. These, together with the recently described Lucheng virus found in China, form a distinct rodent/shrew-specific clade within the coronavirus phylogeny. Across a highly conserved region of the viral polymerase gene, the new members of this clade were up to 22% dissimilar at the nucleotide level to the previously described Lucheng virus. As such they might represent distinct species of alphacoronaviruses. These data greatly extend our knowledge of wildlife reservoirs of alphacoronaviruses. |
| first_indexed | 2025-11-14T19:15:35Z |
| format | Article |
| id | nottingham-32400 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T19:15:35Z |
| publishDate | 2016 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-324002020-05-08T10:30:21Z https://eprints.nottingham.ac.uk/32400/ Discovery of novel alphacoronaviruses in European rodents and shrews Tsoleridis, Theocharis Onianwa, Okechukwu Horncastle, Emma Dayman, Emma Zhu, Miaoran Danjittrong, Taechasit Wachtl, Marta Behnke, Jerzy M. Chapman, Sarah Strong, Victoria Dodds, Phillipa Tarlinton, Rachael E. Ball, Jonathan K. McClure, Patrick Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex araneus and Myodes glareolus. These, together with the recently described Lucheng virus found in China, form a distinct rodent/shrew-specific clade within the coronavirus phylogeny. Across a highly conserved region of the viral polymerase gene, the new members of this clade were up to 22% dissimilar at the nucleotide level to the previously described Lucheng virus. As such they might represent distinct species of alphacoronaviruses. These data greatly extend our knowledge of wildlife reservoirs of alphacoronaviruses. MDPI 2016-03-18 Article PeerReviewed application/pdf en cc_by https://eprints.nottingham.ac.uk/32400/1/html Tsoleridis, Theocharis, Onianwa, Okechukwu, Horncastle, Emma, Dayman, Emma, Zhu, Miaoran, Danjittrong, Taechasit, Wachtl, Marta, Behnke, Jerzy M., Chapman, Sarah, Strong, Victoria, Dodds, Phillipa, Tarlinton, Rachael E., Ball, Jonathan K. and McClure, Patrick (2016) Discovery of novel alphacoronaviruses in European rodents and shrews. Viruses, 8 (3). 84/1-84/9. ISSN 1999-4915 coronaviruses rodents shrews alphacoronavirus http://www.mdpi.com/1999-4915/8/3/84 doi:10.3390/v8030084 doi:10.3390/v8030084 |
| spellingShingle | coronaviruses rodents shrews alphacoronavirus Tsoleridis, Theocharis Onianwa, Okechukwu Horncastle, Emma Dayman, Emma Zhu, Miaoran Danjittrong, Taechasit Wachtl, Marta Behnke, Jerzy M. Chapman, Sarah Strong, Victoria Dodds, Phillipa Tarlinton, Rachael E. Ball, Jonathan K. McClure, Patrick Discovery of novel alphacoronaviruses in European rodents and shrews |
| title | Discovery of novel alphacoronaviruses in European
rodents and shrews |
| title_full | Discovery of novel alphacoronaviruses in European
rodents and shrews |
| title_fullStr | Discovery of novel alphacoronaviruses in European
rodents and shrews |
| title_full_unstemmed | Discovery of novel alphacoronaviruses in European
rodents and shrews |
| title_short | Discovery of novel alphacoronaviruses in European
rodents and shrews |
| title_sort | discovery of novel alphacoronaviruses in european
rodents and shrews |
| topic | coronaviruses rodents shrews alphacoronavirus |
| url | https://eprints.nottingham.ac.uk/32400/ https://eprints.nottingham.ac.uk/32400/ https://eprints.nottingham.ac.uk/32400/ |