Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement
Simultaneous EEG-fMRI provides an increasingly attractive research tool to investigate cognitive processes with high temporal and spatial resolution. However, artifacts in EEG data introduced by the MR-scanner still remain a major obstacle. This study employing commonly used artifact correction step...
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| Format: | Article |
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Elsevier
2016
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| Online Access: | https://eprints.nottingham.ac.uk/32369/ |
| _version_ | 1848794392778768384 |
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| author | Fellner, M.-C. Volberg, G. Mullinger, K.J. Goldhacker, M. Wimber, M. Greenlee, M.W. Hanslmayr, S. |
| author_facet | Fellner, M.-C. Volberg, G. Mullinger, K.J. Goldhacker, M. Wimber, M. Greenlee, M.W. Hanslmayr, S. |
| author_sort | Fellner, M.-C. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Simultaneous EEG-fMRI provides an increasingly attractive research tool to investigate cognitive processes with high temporal and spatial resolution. However, artifacts in EEG data introduced by the MR-scanner still remain a major obstacle. This study employing commonly used artifact correction steps shows that head motion, one overlooked major source of artifacts in EEG-fMRI data, can cause plausible EEG effects and EEG-BOLD correlations. Specifically, low frequency EEG (<20 Hz) is strongly correlated with in-scanner movement. Accordingly, minor head motion (<0.2 mm) induces spurious effects in a twofold manner: Small differences in task-correlated motion elicit spurious low frequency effects, and, as motion concurrently influences fMRI data, EEG-BOLD correlations closely match motion-fMRI correlations. We demonstrate these effects in a memory encoding experiment showing that obtained theta power (~3-7 Hz) effects and channel-level theta-BOLD correlations reflect motion in the scanner. These findings highlight an important caveat that needs to be addressed by future EEG-fMRI studies.
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| first_indexed | 2025-11-14T19:15:28Z |
| format | Article |
| id | nottingham-32369 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:15:28Z |
| publishDate | 2016 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-323692024-08-15T15:19:30Z https://eprints.nottingham.ac.uk/32369/ Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement Fellner, M.-C. Volberg, G. Mullinger, K.J. Goldhacker, M. Wimber, M. Greenlee, M.W. Hanslmayr, S. Simultaneous EEG-fMRI provides an increasingly attractive research tool to investigate cognitive processes with high temporal and spatial resolution. However, artifacts in EEG data introduced by the MR-scanner still remain a major obstacle. This study employing commonly used artifact correction steps shows that head motion, one overlooked major source of artifacts in EEG-fMRI data, can cause plausible EEG effects and EEG-BOLD correlations. Specifically, low frequency EEG (<20 Hz) is strongly correlated with in-scanner movement. Accordingly, minor head motion (<0.2 mm) induces spurious effects in a twofold manner: Small differences in task-correlated motion elicit spurious low frequency effects, and, as motion concurrently influences fMRI data, EEG-BOLD correlations closely match motion-fMRI correlations. We demonstrate these effects in a memory encoding experiment showing that obtained theta power (~3-7 Hz) effects and channel-level theta-BOLD correlations reflect motion in the scanner. These findings highlight an important caveat that needs to be addressed by future EEG-fMRI studies. Keywords: Elsevier 2016-06-02 Article PeerReviewed Fellner, M.-C., Volberg, G., Mullinger, K.J., Goldhacker, M., Wimber, M., Greenlee, M.W. and Hanslmayr, S. (2016) Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement. NeuroImage, 133 . pp. 354-366. ISSN 1053-8119 Brain oscillations EEG-BOLD correlations motion artifacts simultaneous EEG-fMRI theta oscillations http://www.sciencedirect.com/science/article/pii/S1053811916002366 doi:10.1016/j.neuroimage.2016.03.031 doi:10.1016/j.neuroimage.2016.03.031 |
| spellingShingle | Brain oscillations EEG-BOLD correlations motion artifacts simultaneous EEG-fMRI theta oscillations Fellner, M.-C. Volberg, G. Mullinger, K.J. Goldhacker, M. Wimber, M. Greenlee, M.W. Hanslmayr, S. Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement |
| title | Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement |
| title_full | Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement |
| title_fullStr | Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement |
| title_full_unstemmed | Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement |
| title_short | Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement |
| title_sort | spurious correlations in simultaneous eeg-fmri driven by in-scanner movement |
| topic | Brain oscillations EEG-BOLD correlations motion artifacts simultaneous EEG-fMRI theta oscillations |
| url | https://eprints.nottingham.ac.uk/32369/ https://eprints.nottingham.ac.uk/32369/ https://eprints.nottingham.ac.uk/32369/ |