Cyclin A1 and P450 aromatase promote metastatic homing and growth of stem-like prostate cancer cells in the bone marrow

Cyclin A1 and P450 aromatase promote metastatic homing and growth of stem-like prostate cancer cells in the bone marrow

Bone metastasis is a leading cause of morbidity and mortality in prostate cancer (PCa). While cancer stem-like cells have been implicated as a cell of origin for PCa metastases, the pathways which enable metastatic development at distal sites remain largely unknown. In this study, we illuminate path...

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Bibliographic Details
Main Authors: Miftakhova, Regina, Hedblom, Andreas, Semenas, Julius, Robinson, Brian D., Simoulis, Athanasios, Malm, Johan, Rizvanov, Albert, David Heery, David, Mongan, Nigel P., Maitland, Norman J., Allegrucci, Cinzia, Persson, Jenny L.
Format: Article
Published: American Association for Cancer Research 2016
Online Access:https://eprints.nottingham.ac.uk/32025/

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