Biological significance of human epidermal growth factor receptor 2 (HER2) in breast cancer: effect of oestrogen receptor

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Biological significance of human epidermal growth factor receptor 2 (HER2) in breast cancer: effect of oestrogen receptor

Background: HER2 gene amplification and protein overexpression defined as HER2 positivity (HER2+) breast cancer (BC) is encountered in 15-25% of cases and is characterised by an aggressive behaviour and poor outcome. Despite the high clinical efficacy of anti-HER2 targeted therapy, the response...

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Bibliographic Details
Main Author:	Ahmad, Dena Akram Jerjees
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	Epidermal growth factor receptors Oestrogen receptors HER2
Online Access:	https://eprints.nottingham.ac.uk/31918/

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