Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma

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Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma

Introduction: The median survival of patients with glioblastoma multiforme (astrocytoma grade 4) remains less than 18 months despite radical surgery, radiotherapy and systemic chemotherapy. Surgical implantation of chemotherapy eluting wafers into the resection cavity has been shown to improve lengt...

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Bibliographic Details
Main Authors:	Smith, Stuart J., Rahman, Cheryl V., Clarke, P.A., Ritchie, A.A., Gould, Toby W.A., Ward, Jennifer H., Shakesheff, Kevin M., Grundy, Richard G., Rahman, Ruman
Format:	Article
Published:	Royal College of Surgeons of England 2014
Subjects:	Glioblastoma Drug delivery systems Neurosurgery
Online Access:	https://eprints.nottingham.ac.uk/31796/

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