Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma
Introduction: The median survival of patients with glioblastoma multiforme (astrocytoma grade 4) remains less than 18 months despite radical surgery, radiotherapy and systemic chemotherapy. Surgical implantation of chemotherapy eluting wafers into the resection cavity has been shown to improve lengt...
| Main Authors: | Smith, Stuart J., Rahman, Cheryl V., Clarke, Alison A., Gould, Toby W., Ward, Jennifer H., Shakesheff, Kevin M., Grundy, Richard G., Rahman, Ruman |
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| Format: | Article |
| Published: |
Royal College of Surgeons of England
2014
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/31766/ |
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