Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
Pseudomonas aeruginosa chronically infects patients with cystic fibrosis and is associated with greater morbidity. There has been limited progress on the clinical development of new antibiotics with novel modes of action. This review addresses some of the latest research developments on the exploita...
| Main Authors: | Hurley, M.N., Cámara, Miguel, Smyth, Alan R. |
|---|---|
| Format: | Article |
| Published: |
European Respiratory Society
2012
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/3173/ |
Similar Items
Results of antibiotic susceptibility testing do not influence clinical outcome in children with cystic fibrosis
by: Hurley, M.N., et al.
Published: (2012)
by: Hurley, M.N., et al.
Published: (2012)
Early respiratory bacterial detection and anti-staphylococcal antibiotic prophylaxis in young children with cystic fibrosis
by: Hurley, Matthew, et al.
Published: (2017)
by: Hurley, Matthew, et al.
Published: (2017)
A phase 3, open-label, randomized trial to evaluate the safety and efficacy of levofloxacin inhalation solution (APT-1026) versus tobramycin inhalation solution in stable cystic fibrosis patients
by: Elborn, J. Stuart, et al.
Published: (2015)
by: Elborn, J. Stuart, et al.
Published: (2015)
A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients
by: Flume, Patrick, et al.
Published: (2016)
by: Flume, Patrick, et al.
Published: (2016)
Lectin-mediated biofilm maturation, quorum sensing and Pseudomonas aeruginosa infections in cystic fibrosis
by: Crusz, S.A.
Published: (2009)
by: Crusz, S.A.
Published: (2009)
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis
by: Langton Hewer, Simon C., et al.
Published: (2014)
by: Langton Hewer, Simon C., et al.
Published: (2014)
An ex vivo lung model to study bronchioles infected with Pseudomonas aeruginosa biofilms
by: Harrison, Freya, et al.
Published: (2016)
by: Harrison, Freya, et al.
Published: (2016)
Mitigating the harm caused by Pseudomonas aeruginosa in Cystic Fibrosis
by: Palser, Sally C.
Published: (2024)
by: Palser, Sally C.
Published: (2024)
Interventions for the eradication of meticillin-resistant
Staphylococcus aureus (MRSA) in people with cystic fibrosis
by: Smyth, Alan R.
Published: (2015)
by: Smyth, Alan R.
Published: (2015)
Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium
by: Freschi, Luca, et al.
Published: (2015)
by: Freschi, Luca, et al.
Published: (2015)
Metabolic functions of the Pseudomonas aeruginosa aminoglycoside resistance gene, aph
by: Aksoy, Cemile Selin
Published: (2024)
by: Aksoy, Cemile Selin
Published: (2024)
Surviving and thriving in the cystic fibrosis lung: contribution of an arginine specific aminopeptidase to sustained infection by Pseudomonas aeruginosa
by: Spencer, Daniella Lucy
Published: (2019)
by: Spencer, Daniella Lucy
Published: (2019)
Glutamine supplementation in cystic fibrosis: a randomized placebo-controlled trial
by: Forrester, Doug L., et al.
Published: (2015)
by: Forrester, Doug L., et al.
Published: (2015)
Delayed publications of clinical trials in cystic fibrosis
by: Hurley, M.N., et al.
Published: (2011)
by: Hurley, M.N., et al.
Published: (2011)
Domain swapping to generate new antibiotic proteins
by: Kapp, James
Published: (2024)
by: Kapp, James
Published: (2024)
Tackling antimicrobial resistance through two novel methods: repurposing vanoxerine as a novel anti-tubercular drug; and silencing virulence in Pseudomonas aeruginosa through inhibition of PqsR
by: Grossman, Scott
Published: (2018)
by: Grossman, Scott
Published: (2018)
European Cystic Fibrosis Society standards of care: best practice guidelines
by: Smyth, Alan R., et al.
Published: (2014)
by: Smyth, Alan R., et al.
Published: (2014)
The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and health care providers
by: Rowbotham, Nicola J., et al.
Published: (2017)
by: Rowbotham, Nicola J., et al.
Published: (2017)
The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: a randomised comparison
by: Prayle, A.P., et al.
Published: (2015)
by: Prayle, A.P., et al.
Published: (2015)
Working with the patient and clinical community to deliver clinical research in cystic fibrosis. James Lind CF Phase II
by: Smith, S.J., et al.
Published: (2018)
by: Smith, S.J., et al.
Published: (2018)
Molecular studies of antibiotic resistance among the clinical isolates of pseudomonas aeruginosa isolated in Selayang Hospital, Malaysia / Md. Fazlul Karim Khan
by: Karim Khan, Md. Fazlul
Published: (2015)
by: Karim Khan, Md. Fazlul
Published: (2015)
Xbox Kinect™ represents high intensity exercise for adults with cystic fibrosis
by: Holmes, H., et al.
Published: (2013)
by: Holmes, H., et al.
Published: (2013)
Measures of body habitus are associated with lung function in adults with cystic fibrosis: a population-based study
by: Forrester, Doug L., et al.
Published: (2013)
by: Forrester, Doug L., et al.
Published: (2013)
Airway infection and Pseudomonas aeruginosa in bronchiectasis (cystic fibrosis and non-cystic fibrosis bronchiectasis)
by: Webb, Karmel
Published: (2022)
by: Webb, Karmel
Published: (2022)
High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection
by: Monaghan, Tanya M., et al.
Published: (2017)
by: Monaghan, Tanya M., et al.
Published: (2017)
Molecular characterization and antibiotic susceptibility of methicillin resistant staphylococcus aureus isolated from chickens and cattle
by: Magashi, Abbulkadir Magaji
Published: (2012)
by: Magashi, Abbulkadir Magaji
Published: (2012)
Antimicrobials and antimicrobial resistance (AAMR)
by: Papangeli, Maria
Published: (2018)
by: Papangeli, Maria
Published: (2018)
Understanding the Costs of Care for Cystic Fibrosis: an Analysis by Age and Health State
by: Van Gool, K., et al.
Published: (2013)
by: Van Gool, K., et al.
Published: (2013)
Cost-Effectiveness of Carrier Screening for Cystic Fibrosis in Australia
by: Norman, Richard, et al.
Published: (2012)
by: Norman, Richard, et al.
Published: (2012)
Prescribing practices for intravenous aminoglycosides in UK cystic fibrosis clinics: a questionnaire survey
by: Smyth, Alan R., et al.
Published: (2014)
by: Smyth, Alan R., et al.
Published: (2014)
Antimicrobials and Antimicrobial Resistance (AAMR)
by: Blower, Isobel
Published: (2019)
by: Blower, Isobel
Published: (2019)
Synthesis and biological evaluation of novel PqsR antagonists
to combat Pseudomonas aeruginosa infections
by: Mashabi, Alaa
Published: (2021)
by: Mashabi, Alaa
Published: (2021)
Prevention of treatment related adverse effects in cystic fibrosis
by: Jain, Kamini
Published: (2018)
by: Jain, Kamini
Published: (2018)
Use of a primary epithelial cell screening tool to investigate phage therapy in cystic fibrosis
by: Trend, S., et al.
Published: (2018)
by: Trend, S., et al.
Published: (2018)
2 research projects looking at different methods of combatting antibiotic resistance
by: Fenn, S.J.
Published: (2017)
by: Fenn, S.J.
Published: (2017)
Understanding chronic inflammatory diseases in the human lung: the cystic fibrosis and idiopathic pulmonary fibrosis paradigms
by: Liu, Yi-Chia
Published: (2014)
by: Liu, Yi-Chia
Published: (2014)
Public health messages about antibiotic treatment for respiratory tract infection may increase perceived symptom severity reporting
by: Lawrence, Claire, et al.
Published: (2016)
by: Lawrence, Claire, et al.
Published: (2016)
Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis.
by: Thomson, E., et al.
Published: (2010)
by: Thomson, E., et al.
Published: (2010)
Antimicrobials and antimicrobial resistance
by: Lyons, Kevin
Published: (2018)
by: Lyons, Kevin
Published: (2018)
Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf
by: Mohammad Yusuf, Shafinaz
Published: (2015)
by: Mohammad Yusuf, Shafinaz
Published: (2015)
Similar Items
-
Results of antibiotic susceptibility testing do not influence clinical outcome in children with cystic fibrosis
by: Hurley, M.N., et al.
Published: (2012) -
Early respiratory bacterial detection and anti-staphylococcal antibiotic prophylaxis in young children with cystic fibrosis
by: Hurley, Matthew, et al.
Published: (2017) -
A phase 3, open-label, randomized trial to evaluate the safety and efficacy of levofloxacin inhalation solution (APT-1026) versus tobramycin inhalation solution in stable cystic fibrosis patients
by: Elborn, J. Stuart, et al.
Published: (2015) -
A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients
by: Flume, Patrick, et al.
Published: (2016) -
Lectin-mediated biofilm maturation, quorum sensing and Pseudomonas aeruginosa infections in cystic fibrosis
by: Crusz, S.A.
Published: (2009)