Synergism between cAMP and PPARγ signalling in the initiation of UCP1 gene expression in HIB1B brown adipocytes

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Synergism between cAMP and PPARγ signalling in the initiation of UCP1 gene expression in HIB1B brown adipocytes

Expression of the brown adipocyte-specific gene, uncoupling protein 1 (UCP1), is increased by both PPAR stimulation and cAMP activation through their ability to stimulate the expression of the PPAR coactivator PGC1. In HIB1B brown preadipocytes, combination of the PPAR agonist, rosiglitazone, and th...

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Bibliographic Details
Main Authors:	Chen, H.Y., Liu, Q., Salter, Andrew M., Lomax, Michael A.
Format:	Article
Published:	Hindawi Publishing Corporation 2013
Online Access:	https://eprints.nottingham.ac.uk/3170/

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