Synthesis of spirocyclic enones by rhodium-catalyzed dearomatizing oxidative annulation of 2-alkenylphenols with alkynes and enynes

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Synthesis of spirocyclic enones by rhodium-catalyzed dearomatizing oxidative annulation of 2-alkenylphenols with alkynes and enynes

The dearomatizing oxidative annulation of 2-alkenylphenols with alkynes and enynes proceeds with high yields and regioselectivities under Rh(III) catalysis. These reactions are successful using Cu(OAc)2 or air as the stoichiometric oxidant, and provide spirocyclic enones, the basic ring system of wh...

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Bibliographic Details
Main Authors:	Kujawa, Szymon, Best, Daniel, Burns, David J., Lam, Hon Wai
Format:	Article
Published:	Wiley-VCH Verlag 2014
Online Access:	https://eprints.nottingham.ac.uk/31657/

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