Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma

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Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma

Purpose: Asthma is a disease of increasing worldwide importance that calls for new investigative methods. Ex vivo lung tissue is being increasingly used to study functional respiratory parameters independent of confounding systemic considerations but also to reduce animal numbers and associated rese...

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Bibliographic Details
Main Authors:	Lilburn, David M.L., Tatler, Amanda L., Six, Joseph S., Lesbats, Clémentine, Habgood, Antony, Porte, Joanne, Hughes-Riley, Theodore, Shaw, Dominick E., Jenkins, Gisli, Meersmann, Thomas
Format:	Article
Published:	Wiley 2015
Subjects:	pulmonary imaging; hyperpolarized noble gas MRI; hp 129Xe; ovalbumin (OVA) rat model of asthma; methacholine challenges; airway hyper-responsiveness
Online Access:	https://eprints.nottingham.ac.uk/31552/

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