Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer

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Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer

A new approach for hyperpolarized 129Xe molecular sensors is explored using paramagnetic relaxation agents that can be deactivated upon chemical or enzymatic reaction with an analyte. Cryptophane encapsulated 129Xe within the vicinity of the paramagnetic center experiences fast relaxation that, thro...

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Bibliographic Details
Main Authors:	Zamberlan, Francesco, Lesbats, Clémentine, Rogers, Nicola J., Krupa, James L., Pavlovskaya, Galina E., Thomas, Neil R., Faas, Henryk, Meersmann, Thomas
Format:	Article
Published:	Wiley-VCH 2015
Subjects:	Hyperpolarized xenon biosensor • MRI contrast agent • cryptophane • HyperCEST • molecular imaging
Online Access:	https://eprints.nottingham.ac.uk/31550/

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