A 2-year randomised placebo-controlled trial of doxycycline for lymphangioleiomyomatosis

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A 2-year randomised placebo-controlled trial of doxycycline for lymphangioleiomyomatosis

Lymphangioleiomyomatosis (LAM) is characterised by lung cysts and airflow obstruction. Matrix metalloproteinases have been implicated in lung destruction in LAM. We performed a randomised, double-blind trial, comparing the matrix metalloproteinases inhibitor doxycycline with placebo on the progressi...

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Bibliographic Details
Main Authors:	Chang, William Y.C., Cane, Jennifer L., Kumaran, Maruti, Lewis, Sarah, Tattersfield, Anne E., Johnson, Simon R.
Format:	Article
Published:	European Respiratory Society 2014
Subjects:	Rare Lung Diseases Lung Proteases Tuberous sclerosis
Online Access:	https://eprints.nottingham.ac.uk/31531/

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