Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial
Background Exercise has been shown to be effective in treating depression, but trials testing the effect of exercise for depressed adolescents utilising mental health services are rare. The aim of this study was to determine the effectiveness of a preferred intensity exercise intervention on the de...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BioMed Central
2015
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/31490/ |
| _version_ | 1848794213789990912 |
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| author | Carter, Tim Guo, Boliang Turner, David Morres, Ioannis Khalil, Elizabeth Brighton, Emily Armstrong, Marie Callaghan, Patrick |
| author_facet | Carter, Tim Guo, Boliang Turner, David Morres, Ioannis Khalil, Elizabeth Brighton, Emily Armstrong, Marie Callaghan, Patrick |
| author_sort | Carter, Tim |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background
Exercise has been shown to be effective in treating depression, but trials testing the effect of exercise for depressed adolescents utilising mental health services are rare. The aim of this study was to determine the effectiveness of a preferred intensity exercise intervention on the depressive symptoms of adolescents with depression.
Methods
We randomly assigned 87 adolescents who were receiving treatment for depression to either 12 sessions of aerobic exercise at preferred intensity alongside treatment as usual or treatment as usual only. The primary outcome was depressive symptom change using the Children’s Depression Inventory 2nd Version (CDI-2) at post intervention. Secondary outcomes were health-related quality of life and physical activity rates. Outcomes were taken at baseline, post intervention and at six month follow up.
Results
CDI-2 score reduction did not differ significantly between groups at post-intervention (est. 95 % CI −6.82, 1.68, p = 0.23). However, there was a difference in CDI-2 score reduction at six month follow-up in favour of the intervention of −4.81 (est. 95 % CI −9.49, −0.12, p = 0.03). Health-related quality of life and physical activity rates did not differ significantly between groups at post-intervention and follow-up.
Conclusions
There was no additional effect of preferred intensity exercise alongside treatment as usual on depressive reduction immediately post intervention. However, effects were observed at six months post-intervention, suggesting a delayed response. However, further trials, with larger samples are required to determine the validity of this finding.
Trial registration
ClinicalTrials.gov NCT01474837, March 16 2011 |
| first_indexed | 2025-11-14T19:12:37Z |
| format | Article |
| id | nottingham-31490 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T19:12:37Z |
| publishDate | 2015 |
| publisher | BioMed Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-314902020-05-08T10:30:28Z https://eprints.nottingham.ac.uk/31490/ Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial Carter, Tim Guo, Boliang Turner, David Morres, Ioannis Khalil, Elizabeth Brighton, Emily Armstrong, Marie Callaghan, Patrick Background Exercise has been shown to be effective in treating depression, but trials testing the effect of exercise for depressed adolescents utilising mental health services are rare. The aim of this study was to determine the effectiveness of a preferred intensity exercise intervention on the depressive symptoms of adolescents with depression. Methods We randomly assigned 87 adolescents who were receiving treatment for depression to either 12 sessions of aerobic exercise at preferred intensity alongside treatment as usual or treatment as usual only. The primary outcome was depressive symptom change using the Children’s Depression Inventory 2nd Version (CDI-2) at post intervention. Secondary outcomes were health-related quality of life and physical activity rates. Outcomes were taken at baseline, post intervention and at six month follow up. Results CDI-2 score reduction did not differ significantly between groups at post-intervention (est. 95 % CI −6.82, 1.68, p = 0.23). However, there was a difference in CDI-2 score reduction at six month follow-up in favour of the intervention of −4.81 (est. 95 % CI −9.49, −0.12, p = 0.03). Health-related quality of life and physical activity rates did not differ significantly between groups at post-intervention and follow-up. Conclusions There was no additional effect of preferred intensity exercise alongside treatment as usual on depressive reduction immediately post intervention. However, effects were observed at six months post-intervention, suggesting a delayed response. However, further trials, with larger samples are required to determine the validity of this finding. Trial registration ClinicalTrials.gov NCT01474837, March 16 2011 BioMed Central 2015-10-14 Article NonPeerReviewed application/pdf en cc_by https://eprints.nottingham.ac.uk/31490/1/s12888-015-0638-z Carter, Tim, Guo, Boliang, Turner, David, Morres, Ioannis, Khalil, Elizabeth, Brighton, Emily, Armstrong, Marie and Callaghan, Patrick (2015) Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial. BMC Psychiatry, 15 (247). ISSN 1471-244X Depression Adolescence Young people Exercise Physical activity RCT http://dx.doi.org/10.1186/s12888-015-0638-z doi:10.1186/s12888-015-0638-z doi:10.1186/s12888-015-0638-z |
| spellingShingle | Depression Adolescence Young people Exercise Physical activity RCT Carter, Tim Guo, Boliang Turner, David Morres, Ioannis Khalil, Elizabeth Brighton, Emily Armstrong, Marie Callaghan, Patrick Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial |
| title | Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial |
| title_full | Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial |
| title_fullStr | Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial |
| title_full_unstemmed | Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial |
| title_short | Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial |
| title_sort | preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial |
| topic | Depression Adolescence Young people Exercise Physical activity RCT |
| url | https://eprints.nottingham.ac.uk/31490/ https://eprints.nottingham.ac.uk/31490/ https://eprints.nottingham.ac.uk/31490/ |