Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides

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Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides

Protein transduction domains (PTDs) are powerful nongenetic tools that allow intracellular delivery of conjugated cargoes to modify cell behavior. Their use in biomedicine has been hampered by inefficient delivery to nuclear and cytoplasmic targets. Here we overcame this deficiency by developing a s...

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Bibliographic Details
Main Authors:	Dixon, James E., Osman, Gizem, Morris, Gavin E., Markides, Hareklea, Rotherham, Michael, Bayoussef, Zahia, El-Haj, Alicia, Denning, Chris, Shakesheff, Kevin M.
Format:	Article
Published:	National Academy of Sciences 2016
Online Access:	https://eprints.nottingham.ac.uk/31456/

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