Up-regulation of genes involved in the Insulin signaling pathway (IGF1, PTEN and IGFBP1) in the endometrium may link Polycystic Ovarian Syndrome and endometrial cancer

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Up-regulation of genes involved in the Insulin signaling pathway (IGF1, PTEN and IGFBP1) in the endometrium may link Polycystic Ovarian Syndrome and endometrial cancer

BACKGROUND Endometrial cancer (EC) is the most common gynaecological cancer amongst women in the UK. Although previous studies have found that women with polycystic ovary syndrome (PCOS) have at least a three-fold increase in endometrial cancer (EC) risk compared to women without PCOS, the precis...

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Bibliographic Details
Main Authors:	Shafiee, Mohamad Nasir, Seedhouse, Claire, Mongan, Nigel, Chapman, Caroline, Deen, Suha, Abu, Jafaru, Atiomo, William
Format:	Article
Published:	Elsevier 2016
Subjects:	Endometrial cancer; IGF1; IGFBP1; PCOS; PTEN
Online Access:	https://eprints.nottingham.ac.uk/31393/

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