Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

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Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

The adaptive prokaryotic immune system CRISPR-Cas provides RNA-mediated protection from invading genetic elements. The fundamental basis of the system is the ability to capture small pieces of foreign DNA for incorporation into the genome at the CRISPR locus, a process known as Adaptation, which is...

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Bibliographic Details
Main Authors:	Rollie, Clare, Schneider, Stefanie, Brinkmann, Anna Sophie, Bolt, Edward L., White, Malcolm F.
Format:	Article
Published:	eLife Sciences Publications 2015
Online Access:	https://eprints.nottingham.ac.uk/31325/

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