Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium
Clostridium autoethanogenum is an acetogenic bacterium capable of producing high value commodity chemicals and biofuels from the C1 gases present in synthesis gas. This common industrial waste gas can act as the sole energy and carbon source for the bacterium that converts the low value gaseous comp...
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| Format: | Article |
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BioMed Central
2015
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| Online Access: | https://eprints.nottingham.ac.uk/31246/ |
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| author | Humphreys, Christopher M. McLean, Samantha Schatschneider, Sarah Millat, Thomas Henstra, Anne M. Annan, Florence J. Breitkopf, Florence Pander, Bart Piatek, Pawel Rowe, Peter Wichlacz, Alexander T. Woods, Craig Norman, Rupert Blom, Jochen Goesman, Alexander Hodgman, Charlie Barrett, David Thomas, Neil R. Winzer, Klaus Minton, Nigel P. |
| author_facet | Humphreys, Christopher M. McLean, Samantha Schatschneider, Sarah Millat, Thomas Henstra, Anne M. Annan, Florence J. Breitkopf, Florence Pander, Bart Piatek, Pawel Rowe, Peter Wichlacz, Alexander T. Woods, Craig Norman, Rupert Blom, Jochen Goesman, Alexander Hodgman, Charlie Barrett, David Thomas, Neil R. Winzer, Klaus Minton, Nigel P. |
| author_sort | Humphreys, Christopher M. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Clostridium autoethanogenum is an acetogenic bacterium capable of producing high value commodity chemicals and biofuels from the C1 gases present in synthesis gas. This common industrial waste gas can act as the sole energy and carbon source for the bacterium that converts the low value gaseous components into cellular building blocks and industrially relevant products via the action of the reductive acetyl-CoA (Wood-Ljungdahl) pathway. Current research efforts are focused on the enhancement and extension of product formation in this organism via synthetic biology approaches. However, crucial to metabolic modelling and directed pathway engineering is a reliable and comprehensively annotated genome sequence. |
| first_indexed | 2025-11-14T19:11:45Z |
| format | Article |
| id | nottingham-31246 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:11:45Z |
| publishDate | 2015 |
| publisher | BioMed Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-312462020-05-04T17:26:14Z https://eprints.nottingham.ac.uk/31246/ Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium Humphreys, Christopher M. McLean, Samantha Schatschneider, Sarah Millat, Thomas Henstra, Anne M. Annan, Florence J. Breitkopf, Florence Pander, Bart Piatek, Pawel Rowe, Peter Wichlacz, Alexander T. Woods, Craig Norman, Rupert Blom, Jochen Goesman, Alexander Hodgman, Charlie Barrett, David Thomas, Neil R. Winzer, Klaus Minton, Nigel P. Clostridium autoethanogenum is an acetogenic bacterium capable of producing high value commodity chemicals and biofuels from the C1 gases present in synthesis gas. This common industrial waste gas can act as the sole energy and carbon source for the bacterium that converts the low value gaseous components into cellular building blocks and industrially relevant products via the action of the reductive acetyl-CoA (Wood-Ljungdahl) pathway. Current research efforts are focused on the enhancement and extension of product formation in this organism via synthetic biology approaches. However, crucial to metabolic modelling and directed pathway engineering is a reliable and comprehensively annotated genome sequence. BioMed Central 2015-12-21 Article PeerReviewed Humphreys, Christopher M., McLean, Samantha, Schatschneider, Sarah, Millat, Thomas, Henstra, Anne M., Annan, Florence J., Breitkopf, Florence, Pander, Bart, Piatek, Pawel, Rowe, Peter, Wichlacz, Alexander T., Woods, Craig, Norman, Rupert, Blom, Jochen, Goesman, Alexander, Hodgman, Charlie, Barrett, David, Thomas, Neil R., Winzer, Klaus and Minton, Nigel P. (2015) Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium. BMC Genomics, 16 . 1085/1-1085/10. ISSN 1471-2164 Clostridium autoethanogenum Next generation sequencing Acetogen Manual annotation Synthesis gas fermentation http://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-015-2287-5 doi:10.1186/s12864-015-2287-5 doi:10.1186/s12864-015-2287-5 |
| spellingShingle | Clostridium autoethanogenum Next generation sequencing Acetogen Manual annotation Synthesis gas fermentation Humphreys, Christopher M. McLean, Samantha Schatschneider, Sarah Millat, Thomas Henstra, Anne M. Annan, Florence J. Breitkopf, Florence Pander, Bart Piatek, Pawel Rowe, Peter Wichlacz, Alexander T. Woods, Craig Norman, Rupert Blom, Jochen Goesman, Alexander Hodgman, Charlie Barrett, David Thomas, Neil R. Winzer, Klaus Minton, Nigel P. Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium |
| title | Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium |
| title_full | Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium |
| title_fullStr | Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium |
| title_full_unstemmed | Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium |
| title_short | Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium |
| title_sort | whole genome sequence and manual annotation of clostridium autoethanogenum, an industrially relevant bacterium |
| topic | Clostridium autoethanogenum Next generation sequencing Acetogen Manual annotation Synthesis gas fermentation |
| url | https://eprints.nottingham.ac.uk/31246/ https://eprints.nottingham.ac.uk/31246/ https://eprints.nottingham.ac.uk/31246/ |