Catalytic reductive N-alkylation of amines using carboxylic acids
We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids. The two-phase process involves silane mediated direct amidation followed by catalytic reduction.
| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Royal Society of Chemistry
2015
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| Online Access: | https://eprints.nottingham.ac.uk/31067/ |
| _version_ | 1848794121660006400 |
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| author | Andrews, Keith Gordon Summers, Declan Donnelly, Liam Denton, Ross Matthew |
| author_facet | Andrews, Keith Gordon Summers, Declan Donnelly, Liam Denton, Ross Matthew |
| author_sort | Andrews, Keith Gordon |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids. The two-phase process involves silane mediated direct amidation followed by catalytic reduction. |
| first_indexed | 2025-11-14T19:11:10Z |
| format | Article |
| id | nottingham-31067 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:11:10Z |
| publishDate | 2015 |
| publisher | Royal Society of Chemistry |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-310672020-05-04T17:28:08Z https://eprints.nottingham.ac.uk/31067/ Catalytic reductive N-alkylation of amines using carboxylic acids Andrews, Keith Gordon Summers, Declan Donnelly, Liam Denton, Ross Matthew We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids. The two-phase process involves silane mediated direct amidation followed by catalytic reduction. Royal Society of Chemistry 2015-12-03 Article PeerReviewed Andrews, Keith Gordon, Summers, Declan, Donnelly, Liam and Denton, Ross Matthew (2015) Catalytic reductive N-alkylation of amines using carboxylic acids. Chemical Communications . ISSN 1364-548X (In Press) http://pubs.rsc.org/en/content/articlelanding/2015/cc/c5cc08881j#!divAbstract doi:10.1039/C5CC08881J doi:10.1039/C5CC08881J |
| spellingShingle | Andrews, Keith Gordon Summers, Declan Donnelly, Liam Denton, Ross Matthew Catalytic reductive N-alkylation of amines using carboxylic acids |
| title | Catalytic reductive N-alkylation of amines using carboxylic acids |
| title_full | Catalytic reductive N-alkylation of amines using carboxylic acids |
| title_fullStr | Catalytic reductive N-alkylation of amines using carboxylic acids |
| title_full_unstemmed | Catalytic reductive N-alkylation of amines using carboxylic acids |
| title_short | Catalytic reductive N-alkylation of amines using carboxylic acids |
| title_sort | catalytic reductive n-alkylation of amines using carboxylic acids |
| url | https://eprints.nottingham.ac.uk/31067/ https://eprints.nottingham.ac.uk/31067/ https://eprints.nottingham.ac.uk/31067/ |