Design, synthesis and evaluation of inhibitors of POT1-DNA interactions

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Design, synthesis and evaluation of inhibitors of POT1-DNA interactions

The unlimited replicative potential of cells is one of the hallmarks of cancer. Telomeres, DNA structures found at the ends of chromosomes have attracted a great deal of interest in recent years as potential anti-cancer drug targets since they play an important role in cancer cell immortality. Th...

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Bibliographic Details
Main Author:	Malik, Adnan Mahmood
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2013
Online Access:	https://eprints.nottingham.ac.uk/31000/

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