Knockdown of the C. elegans kinome identifies kinases required for normal protein homeostasis, mitochondrial network structure, and sarcomere structure in muscle

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Knockdown of the C. elegans kinome identifies kinases required for normal protein homeostasis, mitochondrial network structure, and sarcomere structure in muscle

Kinases are important signalling molecules for modulating cellular processes and major targets of drug discovery programs. However, functional information for roughly half the human kinome is lacking. We conducted three kinome wide, >90%, RNAi screens and epistasis testing of some identified kina...

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Bibliographic Details
Main Authors:	Lehmann, Susann, Bass, Joseph J., Szewczyk, N.J.
Format:	Article
Published:	BioMed Central 2013
Online Access:	https://eprints.nottingham.ac.uk/3089/

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