3D chemical characterization of frozen hydrated hydrogels using ToF-SIMS with argon cluster sputter depth profiling

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3D chemical characterization of frozen hydrated hydrogels using ToF-SIMS with argon cluster sputter depth profiling

Hydrogels have been used extensively in bioengineering as artificial cell culture supports. Investigation of the interrelationship between cellular response to the hydrogel and its chemistry ideally requires methods that allow characterization without labels and can map species in three dimensional...

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Bibliographic Details
Main Authors:	Taylor, Michael, Scurr, David, Lutolf, Matthias, Buttery, Lee D.K., Zelzer, Mischa, Alexander, Morgan R.
Format:	Article
Published:	American Vacuum Society 2015
Subjects:	Gels Ice Cell Cultures Polymer films Polymers
Online Access:	https://eprints.nottingham.ac.uk/30879/

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