Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2

We present a novel near ambient temperature approach to telechelic renewable polyesters by exploiting the unique properties of supercritical CO2 (scCO2). Bio-based commercially available monomers have been polymerised and functional telechelic materials with targeted molecular weight were prepared b...

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Main Authors: Curia, S., Barclay, A.F., Torron, S., Johansson, M., Howdle, S.M.
Format: Article
Published: Royal Society of Chemistry 2015
Subjects:
Online Access:https://eprints.nottingham.ac.uk/30870/
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author Curia, S.
Barclay, A.F.
Torron, S.
Johansson, M.
Howdle, S.M.
author_facet Curia, S.
Barclay, A.F.
Torron, S.
Johansson, M.
Howdle, S.M.
author_sort Curia, S.
building Nottingham Research Data Repository
collection Online Access
description We present a novel near ambient temperature approach to telechelic renewable polyesters by exploiting the unique properties of supercritical CO2 (scCO2). Bio-based commercially available monomers have been polymerised and functional telechelic materials with targeted molecular weight were prepared by end-capping the chains with molecules containing reactive moieties in a one-pot reaction. The use of scCO2 as a reaction medium facilitates the effective use of Candida Antarctica Lipase B (CaLB) as a catalyst at a temperature as low as 35 °C, hence avoiding side reactions, maintaining the end-capper functionality and preserving the enzyme activity. The functionalised polymer products have been characterised by 1H-NMR, MALDI-TOF, GPC and DSC in order to carefully assess their structural and thermal properties. We demonstrate that telechelic materials can be produced enzymatically at mild temperatures, in a solvent-free system and using renewably sourced monomers without pre-modification, by exploiting the unique properties of scCO2. The macromolecules we prepare are ideal green precursors that can be further reacted to prepare useful bio-derived films and coatings.
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spelling nottingham-308702020-05-04T17:22:54Z https://eprints.nottingham.ac.uk/30870/ Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2 Curia, S. Barclay, A.F. Torron, S. Johansson, M. Howdle, S.M. We present a novel near ambient temperature approach to telechelic renewable polyesters by exploiting the unique properties of supercritical CO2 (scCO2). Bio-based commercially available monomers have been polymerised and functional telechelic materials with targeted molecular weight were prepared by end-capping the chains with molecules containing reactive moieties in a one-pot reaction. The use of scCO2 as a reaction medium facilitates the effective use of Candida Antarctica Lipase B (CaLB) as a catalyst at a temperature as low as 35 °C, hence avoiding side reactions, maintaining the end-capper functionality and preserving the enzyme activity. The functionalised polymer products have been characterised by 1H-NMR, MALDI-TOF, GPC and DSC in order to carefully assess their structural and thermal properties. We demonstrate that telechelic materials can be produced enzymatically at mild temperatures, in a solvent-free system and using renewably sourced monomers without pre-modification, by exploiting the unique properties of scCO2. The macromolecules we prepare are ideal green precursors that can be further reacted to prepare useful bio-derived films and coatings. Royal Society of Chemistry 2015-11-16 Article PeerReviewed Curia, S., Barclay, A.F., Torron, S., Johansson, M. and Howdle, S.M. (2015) Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2. Philosophical Transactions A: Mathematical, Physical and Engineering Sciences, 373 (2057). pp. 1-16. ISSN 1471-2962 Azelaic acid Supercritical CO2 Lipase Telechelics http://rsta.royalsocietypublishing.org/content/373/2057/20150073.abstract doi:10.1098/rsta.2015.0073 doi:10.1098/rsta.2015.0073
spellingShingle Azelaic acid
Supercritical CO2
Lipase
Telechelics
Curia, S.
Barclay, A.F.
Torron, S.
Johansson, M.
Howdle, S.M.
Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2
title Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2
title_full Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2
title_fullStr Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2
title_full_unstemmed Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2
title_short Green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical CO2
title_sort green process for green materials: viable low-temperature lipase-catalysed synthesis of renewable telechelics in supercritical co2
topic Azelaic acid
Supercritical CO2
Lipase
Telechelics
url https://eprints.nottingham.ac.uk/30870/
https://eprints.nottingham.ac.uk/30870/
https://eprints.nottingham.ac.uk/30870/