The role of genetics in pre-eclampsia and potential pharmacogenomic interventions

QR Code

The role of genetics in pre-eclampsia and potential pharmacogenomic interventions

The pregnancy-specific condition pre-eclampsia not only affects the health of mother and baby during pregnancy but also has long-term consequences, increasing the chances of cardiovascular disease in later life. It is accepted that pre-eclampsia has a placental origin, but the pathogenic mechanisms...

Full description

Bibliographic Details
Main Authors:	Williams, Paula Juliet, Morgan, Linda
Format:	Article
Published:	Dove Press 2012
Online Access:	https://eprints.nottingham.ac.uk/3078/

Similar Items

Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia
by: Williams, Paula Juliet, et al.
Published: (2012)

The genetics of pre-eclampsia and other hypertensive disorders of pregnancy
by: Williams, Paula J., et al.
Published: (2011)

Altered placental expression of kisspeptin and its receptor in pre-eclampsia
by: Cartwright, Judith E., et al.
Published: (2012)

Role of oxylipins and small metabolites in pre-eclampsia
by: Sander, Katrin Natsumi
Published: (2016)

Magnetic resonance imaging (MRI) brain findings in severe pre–eclampsia/eclampsia
by: RV, Ganesh, et al.
Published: (2006)

Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia
by: Fitzpatrick, E., et al.
Published: (2009)

Pharmacogenetics, pharmacogenomics and airway disease
by: Hall, Ian P.
Published: (2002)

Inherited factors in pre-eclampsia: Molecular genetic and epidemiological studies in a Sri Lankan population
by: Dissanayake, Vajira Harshadeva Weerabaddana
Published: (2004)

Pre-eclampsia: the role of vascular endothelial growth factor and its interaction with the vascular endothelium
by: Brockelsby, Jeremy Charles
Published: (2001)

Is there any relationship between ABO/Rh blood group and patients with pre-eclampsia?
by: Hentchke, Marta, et al.
Published: (2014)

Targeted mass spectrometry for plasma glycoprotein profiling in pre-eclampsia
by: Dahabiyeh, Lina
Published: (2016)

The placental renin-angiotensin system and oxidative stress in pre-eclampsia
by: Mistry, H.D., et al.
Published: (2013)

Pre-eclampsia and the risk of autism-spectrum disorder in offspring: Meta-analysis
by: Dachew, B., et al.
Published: (2018)

Association between maternal micronutrient status, oxidative stress and common genetic variants in antioxidant enzymes at 15 weeks’ gestation in nulliparous women who subsequently develop pre-eclampsia
by: Mistry, Hiten D., et al.
Published: (2015)

A retrospective study on pre-eclampsia in Hospital Universiti sains Malaysia, Kelantan
by: Mahamooth, Mas Irfan Jaya
Published: (2018)

Genetic dissection of the pre-eclampsia susceptibility locus on chromosome 2q22 reveals shared novel risk factors for cardiovascular disease
by: Johnson, M., et al.
Published: (2013)

Genome-wide transcriptome directed pathway analysis of maternal pre-eclampsia susceptibility genes
by: Yong, H., et al.
Published: (2015)

GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics
by: Tintle, N., et al.
Published: (2018)

Interventionist versus expectant care for severe pre-eclampsia between 24 and 34 weeks' gestation.
by: Churchill, David, et al.
Published: (2013)

Placental expression of eNOS, iNOS and the major protein components of caveolae in women with pre-eclampsia
by: Smith-Jackson, Kate, et al.
Published: (2015)

Pharmacogenomics of drug-induced liver injury (DILI): molecular biology to clinical applications
by: Kaliyaperumal, Kalaiyarasi, et al.
Published: (2018)

Development of a local warfarin dosage guideline based on pharmacogenomics and haemostatic markers
by: An, Chua Yung
Published: (2016)

Overlap of proteomics biomarkers between women with pre-eclampsia and PCOS: a systematic review and biomarker database integration
by: Khan, Gulafshana Hafeez, et al.
Published: (2014)

Increased maternal and fetal cholesterol efflux capacity and placental cyp27a1 expression in pre-eclampsia
by: Mistry, Hiten D., et al.
Published: (2017)

Pre-eclampsia and the risk of attention-deficit/hyperactivity disorder in offspring: Findings from the ALSPAC birth cohort study
by: Dachew, B., et al.
Published: (2019)

Association between pre-eclampsia and locally derived traffic-related air pollution: A retrospective cohort study
by: Pereira, Gavin, et al.
Published: (2013)

Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia
by: Lian, I., et al.
Published: (2011)

Increased decidual mRNA expression levels of candidate maternal pre-eclampsia susceptibility genes are associated with clinical severity
by: Yong, H., et al.
Published: (2014)

Knowledge, attitude and perception of final year pharmacy students at Kulliyyah (faculty) of Pharmacy IIUM on pharmacogenomics
by: Zulkifli, Nurul Hamizah, et al.
Published: (2019)

Pharmacogenomics and pharmacometabolomics of selective serotonin reuptake inhibitors in patients with depression at hospitals in the Klang Valley, Malaysia
by: Badamasi, Ibrahim Mohammed
Published: (2019)

Cancer pharmacogenomics: the relevance of genetic profile in optimization drug therapy for azathiopurine and 5-fluorouracil / Prof Madya Dr Teh Lay Kek and Prof Dr Mohd Zaki Salleh
by: Teh, Lay Kek, et al.
Published: (2010)

3 year review of eclampsia cases in Hospital Tengku Ampuan Afzan, Kuantan
by: Mustafa, Kamarul Bahyah, et al.
Published: (2010)

Integrating pharmacogenomics- metabolomics towards realising personalised medicine for colorectal cancer patients treated with 5-fluorouracil / Hazwanie Hashim
by: Hashim, Hazwanie
Published: (2012)

Is the atherosclerotic phenotype of pre-eclamptic placentas due to altered lipoprotein concentrations and placental lipoprotein receptors?: role of a small-for-gestational-age phenotype
by: Hentchke, Marta, et al.
Published: (2013)

Association between the candidate susceptibility gene ACVR2A on chromosome 2q22 and pre-eclampsia in a large Norwegian population-based study (the HUNT study)
by: Roten, L., et al.
Published: (2009)

Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system
by: Kurlak, L.O., et al.
Published: (2015)

Understanding interpatient variation of clinical responses among acute lymphoblastic leukaemia (All) patients treated with 6-mercaptopurine (6-Mp): a pharmacogenomics-metabolomics perspective / Wan Rosalina Wan Rosli
by: Wan Rosli, Wan Rosalina
Published: (2012)

Pre-marital sex among Malay adolescents: counseling interventions
by: Mansor, Norwati
Published: (2013)

Genetic analyses of pre-meiotic DNA replication in Saccharomyces cerevisiae
by: Maddinapudi, Sri L P
Published: (2015)

Analysis of genetic factors influencing alpha-defensin gene expression
by: Necsoiu, Paula Eugenia
Published: (2018)