Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients

Around 5%–10% of newborn babies require some form of resuscitation at birth and heart rate (HR) is the best guide of efficacy. We report the development and first trial of a device that continuously monitors neonatal HR, with a view to deployment in the delivery room to guide newborn resuscitation....

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Main Authors: Grubb, Mark, Carpenter, James, Crowe, John A., Teoh, Jeremy, Marlow, Neil, Ward, Carole, Mann, Chantelle, Sharkey, Don, Hayes-Gill, Barrie R.
Format: Article
Published: Institute of Physics 2014
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Online Access:https://eprints.nottingham.ac.uk/3061/
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author Grubb, Mark
Carpenter, James
Crowe, John A.
Teoh, Jeremy
Marlow, Neil
Ward, Carole
Mann, Chantelle
Sharkey, Don
Hayes-Gill, Barrie R.
author_facet Grubb, Mark
Carpenter, James
Crowe, John A.
Teoh, Jeremy
Marlow, Neil
Ward, Carole
Mann, Chantelle
Sharkey, Don
Hayes-Gill, Barrie R.
author_sort Grubb, Mark
building Nottingham Research Data Repository
collection Online Access
description Around 5%–10% of newborn babies require some form of resuscitation at birth and heart rate (HR) is the best guide of efficacy. We report the development and first trial of a device that continuously monitors neonatal HR, with a view to deployment in the delivery room to guide newborn resuscitation. The device uses forehead reflectance photoplethysmography (PPG) with modulated light and lock-in detection. Forehead fixation has numerous advantages including ease of sensor placement, whilst perfusion at the forehead is better maintained in comparison to the extremities. Green light (525 nm) was used, in preference to the more usual red or infrared wavelengths, to optimize the amplitude of the pulsatile signal. Experimental results are presented showing simultaneous PPG and electrocardiogram (ECG) HRs from babies (n = 77), gestational age 26–42 weeks, on a neonatal intensive care unit. In babies ≥32 weeks gestation, the median reliability was 97.7% at ±10 bpm and the limits of agreement (LOA) between PPG and ECG were +8.39 bpm and −8.39 bpm. In babies <32 weeks gestation, the median reliability was 94.8% at ±10 bpm and the LOA were +11.53 bpm and −12.01 bpm. Clinical evaluation during newborn deliveries is now underway.
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spelling nottingham-30612024-08-15T15:15:25Z https://eprints.nottingham.ac.uk/3061/ Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients Grubb, Mark Carpenter, James Crowe, John A. Teoh, Jeremy Marlow, Neil Ward, Carole Mann, Chantelle Sharkey, Don Hayes-Gill, Barrie R. Around 5%–10% of newborn babies require some form of resuscitation at birth and heart rate (HR) is the best guide of efficacy. We report the development and first trial of a device that continuously monitors neonatal HR, with a view to deployment in the delivery room to guide newborn resuscitation. The device uses forehead reflectance photoplethysmography (PPG) with modulated light and lock-in detection. Forehead fixation has numerous advantages including ease of sensor placement, whilst perfusion at the forehead is better maintained in comparison to the extremities. Green light (525 nm) was used, in preference to the more usual red or infrared wavelengths, to optimize the amplitude of the pulsatile signal. Experimental results are presented showing simultaneous PPG and electrocardiogram (ECG) HRs from babies (n = 77), gestational age 26–42 weeks, on a neonatal intensive care unit. In babies ≥32 weeks gestation, the median reliability was 97.7% at ±10 bpm and the limits of agreement (LOA) between PPG and ECG were +8.39 bpm and −8.39 bpm. In babies <32 weeks gestation, the median reliability was 94.8% at ±10 bpm and the LOA were +11.53 bpm and −12.01 bpm. Clinical evaluation during newborn deliveries is now underway. Institute of Physics 2014-04-17 Article PeerReviewed Grubb, Mark, Carpenter, James, Crowe, John A., Teoh, Jeremy, Marlow, Neil, Ward, Carole, Mann, Chantelle, Sharkey, Don and Hayes-Gill, Barrie R. (2014) Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients. Physiological Measurement, 35 (5). pp. 881-893. ISSN 0967-3334 photoplethysmography neonatal resuscitation heart rate delivery room http://iopscience.iop.org/0967-3334/35/5/881/ doi:10.1088/0967-3334/35/5/881 doi:10.1088/0967-3334/35/5/881
spellingShingle photoplethysmography
neonatal
resuscitation
heart rate
delivery room
Grubb, Mark
Carpenter, James
Crowe, John A.
Teoh, Jeremy
Marlow, Neil
Ward, Carole
Mann, Chantelle
Sharkey, Don
Hayes-Gill, Barrie R.
Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients
title Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients
title_full Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients
title_fullStr Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients
title_full_unstemmed Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients
title_short Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients
title_sort forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients
topic photoplethysmography
neonatal
resuscitation
heart rate
delivery room
url https://eprints.nottingham.ac.uk/3061/
https://eprints.nottingham.ac.uk/3061/
https://eprints.nottingham.ac.uk/3061/