Troubleshooting methods for the generation of novel pseudotyped viruses
A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studies such as determining the cellular targets of the...
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| Format: | Article |
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Future Medicine
2016
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| Online Access: | https://eprints.nottingham.ac.uk/30590/ |
| _version_ | 1848794018515779584 |
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| author | King, Barnabas Temperton, Nigel Grehan, Keith Scott, Simon Wright, Edward Tarr, Alexander W. Daly, Janet M. |
| author_facet | King, Barnabas Temperton, Nigel Grehan, Keith Scott, Simon Wright, Edward Tarr, Alexander W. Daly, Janet M. |
| author_sort | King, Barnabas |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studies such as determining the cellular targets of the envelope protein of the virus as well as identification of potential antiviral compounds and measuring specific antibody responses. In this review, we describe the common methodologies employed to generate PVs, with a focus on approaches to improve the efficacy of PV generation. |
| first_indexed | 2025-11-14T19:09:31Z |
| format | Article |
| id | nottingham-30590 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:09:31Z |
| publishDate | 2016 |
| publisher | Future Medicine |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-305902020-05-04T20:05:20Z https://eprints.nottingham.ac.uk/30590/ Troubleshooting methods for the generation of novel pseudotyped viruses King, Barnabas Temperton, Nigel Grehan, Keith Scott, Simon Wright, Edward Tarr, Alexander W. Daly, Janet M. A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studies such as determining the cellular targets of the envelope protein of the virus as well as identification of potential antiviral compounds and measuring specific antibody responses. In this review, we describe the common methodologies employed to generate PVs, with a focus on approaches to improve the efficacy of PV generation. Future Medicine 2016 Article NonPeerReviewed King, Barnabas, Temperton, Nigel, Grehan, Keith, Scott, Simon, Wright, Edward, Tarr, Alexander W. and Daly, Janet M. (2016) Troubleshooting methods for the generation of novel pseudotyped viruses. Future Virology . pp. 1-35. ISSN 1746-0808 (In Press) Pseudotyped virus pseudotypes pseudoparticles envelope glycoproteins |
| spellingShingle | Pseudotyped virus pseudotypes pseudoparticles envelope glycoproteins King, Barnabas Temperton, Nigel Grehan, Keith Scott, Simon Wright, Edward Tarr, Alexander W. Daly, Janet M. Troubleshooting methods for the generation of novel pseudotyped viruses |
| title | Troubleshooting methods for the generation of novel pseudotyped viruses |
| title_full | Troubleshooting methods for the generation of novel pseudotyped viruses |
| title_fullStr | Troubleshooting methods for the generation of novel pseudotyped viruses |
| title_full_unstemmed | Troubleshooting methods for the generation of novel pseudotyped viruses |
| title_short | Troubleshooting methods for the generation of novel pseudotyped viruses |
| title_sort | troubleshooting methods for the generation of novel pseudotyped viruses |
| topic | Pseudotyped virus pseudotypes pseudoparticles envelope glycoproteins |
| url | https://eprints.nottingham.ac.uk/30590/ |