Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study
Aim: To investigate risk factors for first long-bone fractures in children up to 5 years old in order to provide evidence about which families could benefit from injury prevention interventions. Methods: Population-based matched nested case–control study using The Health Improvement Network, a UK...
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| Format: | Article |
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BMJ
2015
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| Online Access: | https://eprints.nottingham.ac.uk/30552/ |
| _version_ | 1848794009025118208 |
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| author | Baker, Ruth Orton, Elizabeth Tata, Laila J. Kendrick, Denise |
| author_facet | Baker, Ruth Orton, Elizabeth Tata, Laila J. Kendrick, Denise |
| author_sort | Baker, Ruth |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Aim: To investigate risk factors for first long-bone fractures in children up to 5 years old in order to provide evidence about which families could benefit from injury prevention interventions.
Methods: Population-based matched nested case–control study using The Health Improvement Network, a UK primary care research database, 1988–2004. Maternal, household and child risk factors for injury were assessed among 2456 children with long-bone fractures (cases). 23 661controls were matched to cases on general practice. Adjusted ORs and 95% CIs were estimated using conditional logistic regression.
Results: Fractures of long-bones were independently associated with younger maternal age and higher birth order, with children who were the fourth-born in the family, or later, having a threefold greater odds of fracture compared to first-born children (adjusted OR 3.12, 95% CI 2.08 to 4.68). Children over the age of 1 year had a fourfold (13–24 months, adjusted OR 4.09 95% CI 3.51 to 4.76) to fivefold (37+ months, adjusted OR 4.88 95% CI 4.21 to 5.66) increase in the odds of a long-bone fracture compared to children aged 0–12 months. Children in families with a history of maternal alcohol misuse had a raised odds of long-bone fracture (adjusted OR 2.33, 95% CI 1.13 to 4.82) compared to those with no documented history.
Conclusions: Risk factors for long-bone fractures in children less than 5 years old included age above 1 year, increasing birth order, younger maternal age and maternal alcohol misuse. These risk factors should be used to prioritise families and communities for injury prevention interventions. |
| first_indexed | 2025-11-14T19:09:22Z |
| format | Article |
| id | nottingham-30552 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:09:22Z |
| publishDate | 2015 |
| publisher | BMJ |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-305522020-05-04T20:08:47Z https://eprints.nottingham.ac.uk/30552/ Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study Baker, Ruth Orton, Elizabeth Tata, Laila J. Kendrick, Denise Aim: To investigate risk factors for first long-bone fractures in children up to 5 years old in order to provide evidence about which families could benefit from injury prevention interventions. Methods: Population-based matched nested case–control study using The Health Improvement Network, a UK primary care research database, 1988–2004. Maternal, household and child risk factors for injury were assessed among 2456 children with long-bone fractures (cases). 23 661controls were matched to cases on general practice. Adjusted ORs and 95% CIs were estimated using conditional logistic regression. Results: Fractures of long-bones were independently associated with younger maternal age and higher birth order, with children who were the fourth-born in the family, or later, having a threefold greater odds of fracture compared to first-born children (adjusted OR 3.12, 95% CI 2.08 to 4.68). Children over the age of 1 year had a fourfold (13–24 months, adjusted OR 4.09 95% CI 3.51 to 4.76) to fivefold (37+ months, adjusted OR 4.88 95% CI 4.21 to 5.66) increase in the odds of a long-bone fracture compared to children aged 0–12 months. Children in families with a history of maternal alcohol misuse had a raised odds of long-bone fracture (adjusted OR 2.33, 95% CI 1.13 to 4.82) compared to those with no documented history. Conclusions: Risk factors for long-bone fractures in children less than 5 years old included age above 1 year, increasing birth order, younger maternal age and maternal alcohol misuse. These risk factors should be used to prioritise families and communities for injury prevention interventions. BMJ 2015-05 Article PeerReviewed Baker, Ruth, Orton, Elizabeth, Tata, Laila J. and Kendrick, Denise (2015) Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study. Archives of Disease in Childhood, 100 (5). pp. 432-437. ISSN 1468-2044 Risk Factors Long-Bone Fractures Children http://adc.bmj.com/content/100/5/432 doi:10.1136/archdischild-2013-305715 doi:10.1136/archdischild-2013-305715 |
| spellingShingle | Risk Factors Long-Bone Fractures Children Baker, Ruth Orton, Elizabeth Tata, Laila J. Kendrick, Denise Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study |
| title | Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study |
| title_full | Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study |
| title_fullStr | Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study |
| title_full_unstemmed | Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study |
| title_short | Risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study |
| title_sort | risk factors for long-bone fractures in children up to 5 years of age: a nested case–control study |
| topic | Risk Factors Long-Bone Fractures Children |
| url | https://eprints.nottingham.ac.uk/30552/ https://eprints.nottingham.ac.uk/30552/ https://eprints.nottingham.ac.uk/30552/ |