The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis

Background: There is evidence from 2 previous meta-analyses that interventions to promote poison prevention behaviours are effective in increasing a range of poison prevention practices in households with children. The published meta-analyses compared any intervention against a “usual care or no int...

Full description

Bibliographic Details
Main Authors: Achana, Felix A., Sutton, Alex J., Kendrick, Denise, Wynn, Persephone, Young, Ben, Jones, David R., Hubbard, Stephanie J., Cooper, Nicola J.
Format: Article
Published: Public Library of Science 2015
Subjects:
Online Access:https://eprints.nottingham.ac.uk/30542/
_version_ 1848794006342860800
author Achana, Felix A.
Sutton, Alex J.
Kendrick, Denise
Wynn, Persephone
Young, Ben
Jones, David R.
Hubbard, Stephanie J.
Cooper, Nicola J.
author_facet Achana, Felix A.
Sutton, Alex J.
Kendrick, Denise
Wynn, Persephone
Young, Ben
Jones, David R.
Hubbard, Stephanie J.
Cooper, Nicola J.
author_sort Achana, Felix A.
building Nottingham Research Data Repository
collection Online Access
description Background: There is evidence from 2 previous meta-analyses that interventions to promote poison prevention behaviours are effective in increasing a range of poison prevention practices in households with children. The published meta-analyses compared any intervention against a “usual care or no intervention” which potentially limits the usefulness of the analysis to decision makers. We aim to use network meta-analysis to simultaneously evaluate the effectiveness of different interventions to increase prevalence of safe storage of i) Medicines only, ii) Other household products only, iii) Poisons (both medicines and non-medicines), iv) Poisonous plants; and v) Possession of poison control centre (PCC) telephone number in households with children. Methods: Data on the effectiveness of poison prevention interventions was extracted from primary studies identified in 2 newly-undertaken systematic reviews. Effect estimates were pooled across studies using a random effects network meta-analysis model. Results: 28 of the 47 primary studies identified were included in the analysis. Compared to usual care intervention, the intervention with education and low cost/free equipment elements was most effective in promoting safe storage of medicines (odds ratio 2.51, 95% credible interval 1.01 to 6.00) while interventions with education, low cost/free equipment, home safety inspection and fitting components were most effective in promoting safe storage of other household products (2.52, 1.12 to 7.13), safe storage of poisons (11.10, 1.60 to 141.50) and possession of PCC number (38.82, 2.19 to 687.10). No one intervention package was more effective than the others in promoting safe storage of poisonous plants. Conclusion: The most effective interventions varied by poison prevention practice, but education alone was not the most effective intervention for any poison prevention practice. Commissioners and providers of poison prevention interventions should tailor the interventions they commission or provide to the poison prevention practices they wish to promote.
first_indexed 2025-11-14T19:09:20Z
format Article
id nottingham-30542
institution University of Nottingham Malaysia Campus
institution_category Local University
last_indexed 2025-11-14T19:09:20Z
publishDate 2015
publisher Public Library of Science
recordtype eprints
repository_type Digital Repository
spelling nottingham-305422020-05-04T17:06:19Z https://eprints.nottingham.ac.uk/30542/ The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis Achana, Felix A. Sutton, Alex J. Kendrick, Denise Wynn, Persephone Young, Ben Jones, David R. Hubbard, Stephanie J. Cooper, Nicola J. Background: There is evidence from 2 previous meta-analyses that interventions to promote poison prevention behaviours are effective in increasing a range of poison prevention practices in households with children. The published meta-analyses compared any intervention against a “usual care or no intervention” which potentially limits the usefulness of the analysis to decision makers. We aim to use network meta-analysis to simultaneously evaluate the effectiveness of different interventions to increase prevalence of safe storage of i) Medicines only, ii) Other household products only, iii) Poisons (both medicines and non-medicines), iv) Poisonous plants; and v) Possession of poison control centre (PCC) telephone number in households with children. Methods: Data on the effectiveness of poison prevention interventions was extracted from primary studies identified in 2 newly-undertaken systematic reviews. Effect estimates were pooled across studies using a random effects network meta-analysis model. Results: 28 of the 47 primary studies identified were included in the analysis. Compared to usual care intervention, the intervention with education and low cost/free equipment elements was most effective in promoting safe storage of medicines (odds ratio 2.51, 95% credible interval 1.01 to 6.00) while interventions with education, low cost/free equipment, home safety inspection and fitting components were most effective in promoting safe storage of other household products (2.52, 1.12 to 7.13), safe storage of poisons (11.10, 1.60 to 141.50) and possession of PCC number (38.82, 2.19 to 687.10). No one intervention package was more effective than the others in promoting safe storage of poisonous plants. Conclusion: The most effective interventions varied by poison prevention practice, but education alone was not the most effective intervention for any poison prevention practice. Commissioners and providers of poison prevention interventions should tailor the interventions they commission or provide to the poison prevention practices they wish to promote. Public Library of Science 2015-04-20 Article PeerReviewed Achana, Felix A., Sutton, Alex J., Kendrick, Denise, Wynn, Persephone, Young, Ben, Jones, David R., Hubbard, Stephanie J. and Cooper, Nicola J. (2015) The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis. PLoS ONE, 10 (4). e0121122. ISSN 1932-6203 Poison Prevention Behaviours Children Network Meta-Analysis http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121122 doi:10.1371/journal.pone.0121122 doi:10.1371/journal.pone.0121122
spellingShingle Poison
Prevention Behaviours
Children
Network Meta-Analysis
Achana, Felix A.
Sutton, Alex J.
Kendrick, Denise
Wynn, Persephone
Young, Ben
Jones, David R.
Hubbard, Stephanie J.
Cooper, Nicola J.
The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis
title The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis
title_full The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis
title_fullStr The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis
title_full_unstemmed The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis
title_short The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis
title_sort effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis
topic Poison
Prevention Behaviours
Children
Network Meta-Analysis
url https://eprints.nottingham.ac.uk/30542/
https://eprints.nottingham.ac.uk/30542/
https://eprints.nottingham.ac.uk/30542/