Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists

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Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists

β-Adrenoceptor antagonists boast a 50-year use for symptomatic control in numerous cardiovascular diseases. One might expect highly selective antagonists are available for the human β-adrenoceptor subtype involved in these diseases, yet few truly β1-selective molecules exist. To address this clinica...

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Bibliographic Details
Main Authors:	Mistry, Shailesh N., Baker, Jillian G., Fischer, Peter M., Hill, Stephen J., Gardiner, Sheila M., Kellam, Barrie
Format:	Article
Published:	American Chemical Society 2013
Online Access:	https://eprints.nottingham.ac.uk/30316/

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