In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor

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In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor

At present no scientific rationale exists for selecting a particular enabling strategy to formulate a poorly water-soluble drug, although this is crucial as it will influence the in vivo performance of the resulting formulation. This study provides an insight into this complicated decision making pr...

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Bibliographic Details
Main Authors:	Muees, Joke, Scurr, David J., Amssoms, Katie, Annaert, Pieter, Davies, Martyn C., Roberts, Clive J., Mooter, Guy Van den
Format:	Article
Published:	Elsevier 2015
Subjects:	Solid dispersions; PLGA; Microspheres; Controlled release; In vivo
Online Access:	https://eprints.nottingham.ac.uk/30306/

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