Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells

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Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells

Background: Human lung mast cells (HLMCs) infiltrate the airway epithelium and airway smooth muscle (ASM) in asthmatic airways. The mechanism of HLMC adhesion to both cell types is only partly defined, and adhesion is not inhibited by function-blocking anti-Kit and anti-stem cell factor (SCF) antibo...

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Bibliographic Details
Main Authors:	Gough, Kevin C., Maddison, Ben C., Shikotra, Aarti, Moiseeva, Elena P., Yang, Weidong, Jarvis, Shila, Bradding, Peter
Format:	Article
Published:	BioMed Central 2015
Subjects:	Mast cell Airway epithelium Airway smooth muscle Phage display ScFv Kit (CD117)
Online Access:	https://eprints.nottingham.ac.uk/30245/

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