DNA repair in cancer: emerging targets for personalized therapy

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DNA repair in cancer: emerging targets for personalized therapy

Genomic deoxyribonucleic acid (DNA) is under constant threat from endogenous and exogenous DNA damaging agents. Mammalian cells have evolved highly conserved DNA repair machinery to process DNA damage and maintain genomic integrity. Impaired DNA repair is a major driver for carcinogenesis and could...

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Bibliographic Details
Main Authors:	Abbotts, Rachel, Thompson, Nicola, Madhusudan, Srinivasan
Format:	Article
Published:	Dove Medical Press 2014
Online Access:	https://eprints.nottingham.ac.uk/3023/

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