Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants

The group VII ethylene response factors (ERFVIIs) are plant-specific transcription factors that have emerged as important regulators of abiotic and biotic stress responses, in particular, low-oxygen stress. A defining feature of ERFVIIs is their conserved N-terminal domain, which renders them oxygen...

Full description

Bibliographic Details
Main Authors: Gibbs, Daniel J., Vincente Conde, Jorge, Berckhan, Sophie, Prasad, Geeta, Mendiondo, Guillermina M., Holdsworth, Michael J.
Format: Article
Published: American Society of Plant Biologists 2015
Online Access:https://eprints.nottingham.ac.uk/30223/
_version_ 1848793944700223488
author Gibbs, Daniel J.
Vincente Conde, Jorge
Berckhan, Sophie
Prasad, Geeta
Mendiondo, Guillermina M.
Holdsworth, Michael J.
author_facet Gibbs, Daniel J.
Vincente Conde, Jorge
Berckhan, Sophie
Prasad, Geeta
Mendiondo, Guillermina M.
Holdsworth, Michael J.
author_sort Gibbs, Daniel J.
building Nottingham Research Data Repository
collection Online Access
description The group VII ethylene response factors (ERFVIIs) are plant-specific transcription factors that have emerged as important regulators of abiotic and biotic stress responses, in particular, low-oxygen stress. A defining feature of ERFVIIs is their conserved N-terminal domain, which renders them oxygen- and nitric oxide (NO)-dependent substrates of the N-end rule pathway of targeted proteolysis. In the presence of these gases, ERFVIIs are destabilized, whereas an absence of either permits their accumulation; ERFVIIs therefore coordinate plant homeostatic responses to oxygen availability and control a wide range of NO-mediated processes. ERFVIIs have a variety of context-specific protein and gene interaction partners, and also modulate gibberellin and abscisic acid signaling to regulate diverse developmental processes and stress responses. This update discusses recent advances in our understanding of ERFVII regulation and function, highlighting their role as central regulators of gaseous signal transduction at the interface of ethylene, oxygen, and NO signaling.
first_indexed 2025-11-14T19:08:21Z
format Article
id nottingham-30223
institution University of Nottingham Malaysia Campus
institution_category Local University
last_indexed 2025-11-14T19:08:21Z
publishDate 2015
publisher American Society of Plant Biologists
recordtype eprints
repository_type Digital Repository
spelling nottingham-302232020-05-04T17:08:58Z https://eprints.nottingham.ac.uk/30223/ Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants Gibbs, Daniel J. Vincente Conde, Jorge Berckhan, Sophie Prasad, Geeta Mendiondo, Guillermina M. Holdsworth, Michael J. The group VII ethylene response factors (ERFVIIs) are plant-specific transcription factors that have emerged as important regulators of abiotic and biotic stress responses, in particular, low-oxygen stress. A defining feature of ERFVIIs is their conserved N-terminal domain, which renders them oxygen- and nitric oxide (NO)-dependent substrates of the N-end rule pathway of targeted proteolysis. In the presence of these gases, ERFVIIs are destabilized, whereas an absence of either permits their accumulation; ERFVIIs therefore coordinate plant homeostatic responses to oxygen availability and control a wide range of NO-mediated processes. ERFVIIs have a variety of context-specific protein and gene interaction partners, and also modulate gibberellin and abscisic acid signaling to regulate diverse developmental processes and stress responses. This update discusses recent advances in our understanding of ERFVII regulation and function, highlighting their role as central regulators of gaseous signal transduction at the interface of ethylene, oxygen, and NO signaling. American Society of Plant Biologists 2015-05-05 Article PeerReviewed Gibbs, Daniel J., Vincente Conde, Jorge, Berckhan, Sophie, Prasad, Geeta, Mendiondo, Guillermina M. and Holdsworth, Michael J. (2015) Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants. Plant Physiology, 169 (1). pp. 23-31. ISSN 0032-0889 http://www.plantphysiol.org/content/169/1/23 doi:10.​1104/​pp.​15.​00338 doi:10.​1104/​pp.​15.​00338
spellingShingle Gibbs, Daniel J.
Vincente Conde, Jorge
Berckhan, Sophie
Prasad, Geeta
Mendiondo, Guillermina M.
Holdsworth, Michael J.
Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants
title Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants
title_full Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants
title_fullStr Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants
title_full_unstemmed Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants
title_short Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants
title_sort group vii ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants
url https://eprints.nottingham.ac.uk/30223/
https://eprints.nottingham.ac.uk/30223/
https://eprints.nottingham.ac.uk/30223/