Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis

QR Code

Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis

C. difficile infection (CDI) is rarely reported in cystic fibrosis (CF) patients despite frequent hospitalisations and antibiotic usage. Conversely, the prevalence of CDI in inflammatory bowel disease (IBD) has received increased attention. We investigated components of the IgG-specific humoral im...

Full description

Bibliographic Details
Main Authors:	Monaghan, Tanya M., Robins, Adrian, Knox, Alan, Sewell, Herbert F., Mahida, Yashwant R.
Format:	Article
Published:	Public Library of Science 2013
Online Access:	https://eprints.nottingham.ac.uk/2982/

Similar Items

High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection
by: Monaghan, Tanya M., et al.
Published: (2017)

Both, toxin A and toxin B, are important in Clostridium difficile infection
by: Kuehne, Sarah A., et al.
Published: (2011)

Importance of Toxin A, Toxin B, and CDT in virulence of an epidemic Clostridium difficile strain
by: Kuehne, Sarah A., et al.
Published: (2013)

Mucosal cell responses to Clostridium difficile toxins
by: Mullan, Nivette K.
Published: (2011)

Structure-function relationships of Clostridium difficile toxin A
by: Craggs, Joanna K.
Published: (1999)

A recombinant non-toxigenic Clostridioides difficile spore vaccine directed against toxigenic C. difficile
by: Aston, Carl
Published: (2022)

CdtR-mediated regulation of toxin production in Clostridium difficile
by: Bilverstone, Terry W.
Published: (2019)

High prevalence of Clostridium difficile Ribotype 078 in IBD outpatients
by: Monaghan, Tanya M., et al.
Published: (2018)

Understanding the genetic mechanisms of Clostridium difficile toxin regulation and clinical relapse
by: Lister, Michelle M.
Published: (2018)

Clostridium difficile modulates host innate immunity via toxin-independent and dependent mechanism(s)
by: Jafari, Nazilla V., et al.
Published: (2013)

Investigation of the effect of insertional mutation in agr and sigB loci in Clostridium difficile R20291
by: Montfort-Gardeazabal, Jorge M.
Published: (2017)

Serum trace metal concentrations in Clostridium difficile infection and their relationship to disease severity
by: Monaghan, Tanya M., et al.
Published: (2018)

Analysis of the spore germination mechanisms of Clostridium difficile
by: Burns, David Alexander
Published: (2011)

Amino acids utilisation by Clostridium difficile strains
by: Ogbu, H.I.
Published: (2016)

Spore germination and recurrence of clostridioides difficile infection
by: Finch, Lorna
Published: (2020)

Development of an oral vaccine against Clostridioides difficile
by: Karyal, Cansu
Published: (2021)

Clostridium difficile infection: clinico-epidemiological perspective.
by: SYUHADA N,, et al.
Published: (2013)

Exposing hidden putative lipoproteins in Clostridium difficile
by: Griffin, R., et al.
Published: (2017)

Characterisation of phosphotransferase systems (PTS) in Clostridium difficile
by: Bollard, Niall
Published: (2018)

Transposon mutagenesis in RT 078 Clostridioides difficile
by: te Vrugt, Marcel
Published: (2023)

Novel lactoferrin-loaded alginate microbeads display anti-Clostridium difficile defence properties
by: Monaghan, Tanya M., et al.
Published: (2018)

Molecular epidemiology of Clostridium difficile isolated from piglets
by: Putsathit, Papanin, et al.
Published: (2019)

A protein microarray assay for serological determination of antigen-specific antibody responses following Clostridium difficile infection
by: Negm, Ola H., et al.
Published: (2018)

Characterisation of a putative quorum sensing system in Colstridium difficile
by: Patel, Manisha R.
Published: (2011)

The antimicrobial and bile acid mediated control of Clostridium difficile infection
by: Dempster, Andrew William
Published: (2018)

Identification and characterisation of novel bacteriocins active against Clostridioides difficile
by: Chapman, Sarah May Olivia
Published: (2020)

Investigating the bile acid mediated control of Clostridioides difficile infection
by: von Emloh, Louise
Published: (2024)

Profiling humoral immune responses to Clostridium difficile-specific antigens by protein microarray analysis
by: Negm, Ola H., et al.
Published: (2015)

A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea
by: Garsed, Klara, et al.
Published: (2013)

US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis
by: Floto, R. Andres, et al.
Published: (2016)

Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile
by: Dapa, Tanja, et al.
Published: (2013)

Developing a protein subunit oral vaccine against Clostridioides difficile
by: Wood, Liam
Published: (2023)

A review on the effects of probiotics and antibiotics towards Clostridium difficile infections
by: Azman, Hazirah, et al.
Published: (2013)

Airway infection and Pseudomonas aeruginosa in bronchiectasis (cystic fibrosis and non-cystic fibrosis bronchiectasis)
by: Webb, Karmel
Published: (2022)

sTREM-1 is elevated in cystic fibrosis and correlates with proteases
by: Forrester, D.L., et al.
Published: (2017)

Towards development of a liposome-based vaccine to combat Clostridium difficile infection
by: Palazi, Panayiota
Published: (2021)

Identification and characterisation of tail components modulating host range of Clostridium difficile phages
by: Steczynska, Joanna
Published: (2023)

Community-associated Clostridium difficile infection in emergency department patients in Western Australia
by: Collins, D., et al.
Published: (2017)

Expanding the genome editing repertoire in Clostridium difficile for improved studies of sporulation and germination
by: Ingle, Patrick S.
Published: (2018)

Protective antibodies against Clostridium difficile are present in intravenous immunoglobulin and are retained in humans following its administration
by: Negm, Ola H., et al.
Published: (2017)