A review of standard pharmacological therapy for adult asthma - Steps 1 to 5

The aim of pharmacological therapy for asthma is to improve symptoms and lung function and minimise the risk of asthma attacks. The intensity of treatment is based on the level of asthma control and the potential risk of future deterioration. In the British asthma guidelines, treatments are divide...

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Main Authors: Patel, Mitesh Dilipkumar Kantilal, Shaw, Dominick E.
Format: Article
Published: SAGE Publications 2015
Subjects:
Online Access:https://eprints.nottingham.ac.uk/29551/
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author Patel, Mitesh Dilipkumar Kantilal
Shaw, Dominick E.
author_facet Patel, Mitesh Dilipkumar Kantilal
Shaw, Dominick E.
author_sort Patel, Mitesh Dilipkumar Kantilal
building Nottingham Research Data Repository
collection Online Access
description The aim of pharmacological therapy for asthma is to improve symptoms and lung function and minimise the risk of asthma attacks. The intensity of treatment is based on the level of asthma control and the potential risk of future deterioration. In the British asthma guidelines, treatments are divided into Step One to Five, with each Step signifying a need for an increase in therapy in response to symptoms or to prevent exacerbations. Treatments comprise of inhaled or systemic medications. Inhaled therapy includes short-acting and long-acting medication to improve symptoms and inhaled corticosteroids which reduce airway inflammation. Systemic treatments include medications which act on specific biological pathways, such as the leukotriene or IgE pathways, or systemic corticosteroids. In choosing a particular therapy, treatment benefits are balanced by the potential risks of medication-related adverse effects. This review will provide a practical guide to the key pharmacological therapies for adult asthma at Steps One to Five based on British guidelines and consider future options for new treatments.
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spelling nottingham-295512020-05-04T20:08:56Z https://eprints.nottingham.ac.uk/29551/ A review of standard pharmacological therapy for adult asthma - Steps 1 to 5 Patel, Mitesh Dilipkumar Kantilal Shaw, Dominick E. The aim of pharmacological therapy for asthma is to improve symptoms and lung function and minimise the risk of asthma attacks. The intensity of treatment is based on the level of asthma control and the potential risk of future deterioration. In the British asthma guidelines, treatments are divided into Step One to Five, with each Step signifying a need for an increase in therapy in response to symptoms or to prevent exacerbations. Treatments comprise of inhaled or systemic medications. Inhaled therapy includes short-acting and long-acting medication to improve symptoms and inhaled corticosteroids which reduce airway inflammation. Systemic treatments include medications which act on specific biological pathways, such as the leukotriene or IgE pathways, or systemic corticosteroids. In choosing a particular therapy, treatment benefits are balanced by the potential risks of medication-related adverse effects. This review will provide a practical guide to the key pharmacological therapies for adult asthma at Steps One to Five based on British guidelines and consider future options for new treatments. SAGE Publications 2015-05 Article NonPeerReviewed Patel, Mitesh Dilipkumar Kantilal and Shaw, Dominick E. (2015) A review of standard pharmacological therapy for adult asthma - Steps 1 to 5. Chronic Respiratory Disease, 12 (2). pp. 165-176. ISSN 1479-9723 Asthma Beta-agonist Inhaled corticosteroid Pharmacological Step http://crd.sagepub.com/content/12/2/165 doi:10.1177/1479972315573529 doi:10.1177/1479972315573529
spellingShingle Asthma
Beta-agonist
Inhaled corticosteroid
Pharmacological
Step
Patel, Mitesh Dilipkumar Kantilal
Shaw, Dominick E.
A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
title A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
title_full A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
title_fullStr A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
title_full_unstemmed A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
title_short A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
title_sort review of standard pharmacological therapy for adult asthma - steps 1 to 5
topic Asthma
Beta-agonist
Inhaled corticosteroid
Pharmacological
Step
url https://eprints.nottingham.ac.uk/29551/
https://eprints.nottingham.ac.uk/29551/
https://eprints.nottingham.ac.uk/29551/