The role of peroxisome proliferator activated receptor alpha (PPARα) in the effect of piroxicam on colon cancer

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The role of peroxisome proliferator activated receptor alpha (PPARα) in the effect of piroxicam on colon cancer

Studies with APCMin/+ mice and APCMin/+ PPARα-/- mice were undertaken to investigate whether polyp development in the mouse gut was mediated by PPARα. Additionally, the effect of piroxicam treatment dependency on PPARα was assessed. Results showed the number of polyps in the colon was significan...

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Bibliographic Details
Main Author:	McCartney, Karen M.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2015
Subjects:	Peroxisome proliferator activated receptor Colon cancer Piroxicam
Online Access:	https://eprints.nottingham.ac.uk/29153/

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