Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacological modulation

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Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacological modulation

Acute myeloid leukemia (AML) is characterized by the accumulation of immature blood cell precursors in the bone marrow. Pharmacologically overcoming the differentiation block in this condition is an attractive therapeutic avenue, which has achieved success only in a subtype of AML, acute promyelocyt...

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Bibliographic Details
Main Authors:	Orfali, Nina, O'Donovan, Tracey R., Nyhan, Michelle J., Britschgi, Adrian, Tschan, Mario P., Cahill, Mary R., Mongan, Nigel P., Gudas, Lorraine J., McKenna, Sharon L.
Format:	Article
Published:	Elsevier 2015
Subjects:	Differentiation Autophagy Myeloid Leukemia ATRA Promyelocytic Leukemia
Online Access:	https://eprints.nottingham.ac.uk/29073/

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