Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial
Background/Aim: Memory problems are frequently reported in people with multiple sclerosis (MS). These can be debilitating and affect individuals and their families. This sub-group analysis focused on the effectiveness of memory rehabilitation in patients with MS. Methods: Data were extracted from a...
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| Format: | Article |
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Mark Allen Healthcare
2014
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| Online Access: | https://eprints.nottingham.ac.uk/29053/ |
| _version_ | 1848793705692004352 |
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| author | Martin, Kristy-Jane Lincoln, Nadina das Nair, Roshan |
| author_facet | Martin, Kristy-Jane Lincoln, Nadina das Nair, Roshan |
| author_sort | Martin, Kristy-Jane |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background/Aim: Memory problems are frequently reported in people with multiple sclerosis (MS). These can be debilitating and affect individuals and their families. This sub-group analysis focused on the effectiveness of memory rehabilitation in patients with MS.
Methods: Data were extracted from a single blind randomised controlled trial, the ReMiND trial, which also included participants with traumatic brain injury and stroke. Participants were randomly allocated to compensation or restitution treatment programmes, or a self-help control. The programmes were manual-based and comprised two individual and ten group sessions. Outcome measures included assessments of memory, mood and activities of daily living. A total of 39 patients with MS participated in this study (ten males (26%), 29 females (74%); mean±SD age: 48.3±10.8 years). Results: Comparison of groups showed no significant effect of treatment on memory, but there were significant differences between compensation and restitution on self-report symptoms of emotional distress at both 5- (p=0.04) and 7-month (p=0.05) follow-up sessions. The compensation group showed less distress than the restitution group.
Conclusions: Individuals with MS who received compensation memory rehabilitation reported significantly less emotional distress than those who received restitution. Further research is needed to explore why self-reported memory problems did not differ between groups. |
| first_indexed | 2025-11-14T19:04:33Z |
| format | Article |
| id | nottingham-29053 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:04:33Z |
| publishDate | 2014 |
| publisher | Mark Allen Healthcare |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-290532020-05-04T16:59:17Z https://eprints.nottingham.ac.uk/29053/ Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial Martin, Kristy-Jane Lincoln, Nadina das Nair, Roshan Background/Aim: Memory problems are frequently reported in people with multiple sclerosis (MS). These can be debilitating and affect individuals and their families. This sub-group analysis focused on the effectiveness of memory rehabilitation in patients with MS. Methods: Data were extracted from a single blind randomised controlled trial, the ReMiND trial, which also included participants with traumatic brain injury and stroke. Participants were randomly allocated to compensation or restitution treatment programmes, or a self-help control. The programmes were manual-based and comprised two individual and ten group sessions. Outcome measures included assessments of memory, mood and activities of daily living. A total of 39 patients with MS participated in this study (ten males (26%), 29 females (74%); mean±SD age: 48.3±10.8 years). Results: Comparison of groups showed no significant effect of treatment on memory, but there were significant differences between compensation and restitution on self-report symptoms of emotional distress at both 5- (p=0.04) and 7-month (p=0.05) follow-up sessions. The compensation group showed less distress than the restitution group. Conclusions: Individuals with MS who received compensation memory rehabilitation reported significantly less emotional distress than those who received restitution. Further research is needed to explore why self-reported memory problems did not differ between groups. Mark Allen Healthcare 2014-12-03 Article PeerReviewed Martin, Kristy-Jane, Lincoln, Nadina and das Nair, Roshan (2014) Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial. International Journal of Therapy and Rehabilitation, 21 (12). pp. 422-428. ISSN 1741-1645 Multiple sclerosis Memory Rehabilitation Randomised controlled trial http://www.magonlinelibrary.com/doi/10.12968/ijtr.2014.21.12.590 doi:10.12968/ijtr.2014.21.12.590 doi:10.12968/ijtr.2014.21.12.590 |
| spellingShingle | Multiple sclerosis Memory Rehabilitation Randomised controlled trial Martin, Kristy-Jane Lincoln, Nadina das Nair, Roshan Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial |
| title | Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial |
| title_full | Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial |
| title_fullStr | Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial |
| title_full_unstemmed | Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial |
| title_short | Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial |
| title_sort | group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the remind trial |
| topic | Multiple sclerosis Memory Rehabilitation Randomised controlled trial |
| url | https://eprints.nottingham.ac.uk/29053/ https://eprints.nottingham.ac.uk/29053/ https://eprints.nottingham.ac.uk/29053/ |