A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration
A dual thermoresponsive and magnetic colloidal gel matrix is described for enhanced stem-cell culture. The combined properties of the material allow enzyme-free passaging and expansion of mesenchymal stem cells, as well as isolation of cells postculture by the simple process of lowering the temperat...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
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Wiley
2015
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| Online Access: | https://eprints.nottingham.ac.uk/28830/ |
| _version_ | 1848793652863696896 |
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| author | Saeed, Aram Omer Francini, Nora White, Lisa Dixon, James E. Gould, Toby W.A. Rashidi, Hassan Cheikh Al Ghanami, Racha Hruschka, Veronika Redl, Heinz Saunders, Brian R Alexander, Cameron Shakesheff, Kevin |
| author_facet | Saeed, Aram Omer Francini, Nora White, Lisa Dixon, James E. Gould, Toby W.A. Rashidi, Hassan Cheikh Al Ghanami, Racha Hruschka, Veronika Redl, Heinz Saunders, Brian R Alexander, Cameron Shakesheff, Kevin |
| author_sort | Saeed, Aram Omer |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | A dual thermoresponsive and magnetic colloidal gel matrix is described for enhanced stem-cell culture. The combined properties of the material allow enzyme-free passaging and expansion of mesenchymal stem cells, as well as isolation of cells postculture by the simple process of lowering the temperature and applying an external magnetic field. The colloidal gel can be reconfigured with thermal and magnetic stimuli to allow patterning of cells in discrete zones and to control movement of cells within the porous matrix during culture. |
| first_indexed | 2025-11-14T19:03:43Z |
| format | Article |
| id | nottingham-28830 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:03:43Z |
| publishDate | 2015 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-288302020-05-04T20:11:50Z https://eprints.nottingham.ac.uk/28830/ A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration Saeed, Aram Omer Francini, Nora White, Lisa Dixon, James E. Gould, Toby W.A. Rashidi, Hassan Cheikh Al Ghanami, Racha Hruschka, Veronika Redl, Heinz Saunders, Brian R Alexander, Cameron Shakesheff, Kevin A dual thermoresponsive and magnetic colloidal gel matrix is described for enhanced stem-cell culture. The combined properties of the material allow enzyme-free passaging and expansion of mesenchymal stem cells, as well as isolation of cells postculture by the simple process of lowering the temperature and applying an external magnetic field. The colloidal gel can be reconfigured with thermal and magnetic stimuli to allow patterning of cells in discrete zones and to control movement of cells within the porous matrix during culture. Wiley 2015 Article PeerReviewed Saeed, Aram Omer, Francini, Nora, White, Lisa, Dixon, James E., Gould, Toby W.A., Rashidi, Hassan, Cheikh Al Ghanami, Racha, Hruschka, Veronika, Redl, Heinz, Saunders, Brian R, Alexander, Cameron and Shakesheff, Kevin (2015) A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration. Advanced Materials, 27 . pp. 662-668. ISSN 0935-9648 responsive polymers tissue engineering regenerative medicine stem cell culture http://onlinelibrary.wiley.com/doi/10.1002/adma.201403626/full doi:10.1002/adma.201403626 doi:10.1002/adma.201403626 |
| spellingShingle | responsive polymers tissue engineering regenerative medicine stem cell culture Saeed, Aram Omer Francini, Nora White, Lisa Dixon, James E. Gould, Toby W.A. Rashidi, Hassan Cheikh Al Ghanami, Racha Hruschka, Veronika Redl, Heinz Saunders, Brian R Alexander, Cameron Shakesheff, Kevin A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration |
| title | A thermoresponsive and magnetic colloid for 3D cell
expansion and reconfiguration |
| title_full | A thermoresponsive and magnetic colloid for 3D cell
expansion and reconfiguration |
| title_fullStr | A thermoresponsive and magnetic colloid for 3D cell
expansion and reconfiguration |
| title_full_unstemmed | A thermoresponsive and magnetic colloid for 3D cell
expansion and reconfiguration |
| title_short | A thermoresponsive and magnetic colloid for 3D cell
expansion and reconfiguration |
| title_sort | thermoresponsive and magnetic colloid for 3d cell
expansion and reconfiguration |
| topic | responsive polymers tissue engineering regenerative medicine stem cell culture |
| url | https://eprints.nottingham.ac.uk/28830/ https://eprints.nottingham.ac.uk/28830/ https://eprints.nottingham.ac.uk/28830/ |