Frailty predicts trajectories of quality of life over time among British community-dwelling older people

Purpose: To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods: Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at basel...

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Main Authors: Kojima, Gotaro, Iliffe, Steve, Morris, Richard.W., Taniguchi, Yu, Kendrick, Denise, Skelton, Dawn A., Masud, Tahir, Bowling, Ann
Format: Article
Published: Springer International Publishing 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/28315/
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author Kojima, Gotaro
Iliffe, Steve
Morris, Richard.W.
Taniguchi, Yu
Kendrick, Denise
Skelton, Dawn A.
Masud, Tahir
Bowling, Ann
author_facet Kojima, Gotaro
Iliffe, Steve
Morris, Richard.W.
Taniguchi, Yu
Kendrick, Denise
Skelton, Dawn A.
Masud, Tahir
Bowling, Ann
author_sort Kojima, Gotaro
building Nottingham Research Data Repository
collection Online Access
description Purpose: To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods: Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People’s Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty. Results: At baseline, mean age was 73.1 (range 65–90) and 62.0 % were women. Mean FI was 0.17 (range 0.00–0.66), and mean OPQOL was 130.80 (range 93–163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = −47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to −1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL. Conclusions: Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined.
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spelling nottingham-283152020-05-04T17:32:51Z https://eprints.nottingham.ac.uk/28315/ Frailty predicts trajectories of quality of life over time among British community-dwelling older people Kojima, Gotaro Iliffe, Steve Morris, Richard.W. Taniguchi, Yu Kendrick, Denise Skelton, Dawn A. Masud, Tahir Bowling, Ann Purpose: To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods: Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People’s Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty. Results: At baseline, mean age was 73.1 (range 65–90) and 62.0 % were women. Mean FI was 0.17 (range 0.00–0.66), and mean OPQOL was 130.80 (range 93–163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = −47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to −1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL. Conclusions: Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined. Springer International Publishing 2016-01-09 Article PeerReviewed Kojima, Gotaro, Iliffe, Steve, Morris, Richard.W., Taniguchi, Yu, Kendrick, Denise, Skelton, Dawn A., Masud, Tahir and Bowling, Ann (2016) Frailty predicts trajectories of quality of life over time among British community-dwelling older people. Quality of Life Research . ISSN 1573-2649 Community-dwelling Older People Frailty Quality of Life Well-being Primary Care http://link.springer.com/article/10.1007%2Fs11136-015-1213-2 doi:10.1007/s11136-015-1213-2 doi:10.1007/s11136-015-1213-2
spellingShingle Community-dwelling Older People
Frailty
Quality of Life
Well-being
Primary Care
Kojima, Gotaro
Iliffe, Steve
Morris, Richard.W.
Taniguchi, Yu
Kendrick, Denise
Skelton, Dawn A.
Masud, Tahir
Bowling, Ann
Frailty predicts trajectories of quality of life over time among British community-dwelling older people
title Frailty predicts trajectories of quality of life over time among British community-dwelling older people
title_full Frailty predicts trajectories of quality of life over time among British community-dwelling older people
title_fullStr Frailty predicts trajectories of quality of life over time among British community-dwelling older people
title_full_unstemmed Frailty predicts trajectories of quality of life over time among British community-dwelling older people
title_short Frailty predicts trajectories of quality of life over time among British community-dwelling older people
title_sort frailty predicts trajectories of quality of life over time among british community-dwelling older people
topic Community-dwelling Older People
Frailty
Quality of Life
Well-being
Primary Care
url https://eprints.nottingham.ac.uk/28315/
https://eprints.nottingham.ac.uk/28315/
https://eprints.nottingham.ac.uk/28315/