A study of functional selectivity at the cannabinoid type 1 receptor
The cannabinoid CB1 receptor is a G protein-coupled receptor (GPCR) which is important in the regulation of neuronal function, predominately via coupling to heterotrimeric Gi/o proteins. The receptor has also been shown to interact with a variety of other intracellular signalling mediators, includin...
| Main Author: | Priestley, Richard |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2015
|
| Online Access: | https://eprints.nottingham.ac.uk/28296/ |
Similar Items
Effect of cannabinoid receptor ligands on microglial cell functions
by: Hassan, Samia
Published: (2013)
by: Hassan, Samia
Published: (2013)
Novel fenofibrate derivatives as cannabinoid receptor ligands
by: Spencer, Sarah Jane
Published: (2011)
by: Spencer, Sarah Jane
Published: (2011)
Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis
by: Shi, Y., et al.
Published: (2017)
by: Shi, Y., et al.
Published: (2017)
Imaging Cannabinoid Receptors: A Brief Collection of Covalent and Fluorescent Probes for CB1 and CB2 Receptors
by: Hamilton, A.J., et al.
Published: (2021)
by: Hamilton, A.J., et al.
Published: (2021)
Investigating ligand-directed signalling at the cannabinoid receptor 2
by: Hourani, Wafa
Published: (2019)
by: Hourani, Wafa
Published: (2019)
Investigating the molecular basis of biased signalling at cannabinoid receptors
by: Dennis, Morgan Jane
Published: (2023)
by: Dennis, Morgan Jane
Published: (2023)
Structural exploration of cannabinoid receptors using computational methods
by: Murali, Lahari
Published: (2020)
by: Murali, Lahari
Published: (2020)
Cannabinoid CB1 receptor binding and acetylcholinesterase
inhibitory activity of Sceletium tortuosum L.
by: Lubbe, A., et al.
Published: (2010)
by: Lubbe, A., et al.
Published: (2010)
Cannabinoid CB1 receptor binding and acetylcholinesterase
inhibitory activity of Sceletium tortuosum L.
by: Lubbe, Andrea, et al.
Published: (2010)
by: Lubbe, Andrea, et al.
Published: (2010)
Design, synthesis and evaluation of fluorescent CB2 cannabinoid receptor ligands
by: Holt, Christopher James
Published: (2009)
by: Holt, Christopher James
Published: (2009)
The effects of cannabinoids on insulin secretion
by: Anderson, Richard L.
Published: (2011)
by: Anderson, Richard L.
Published: (2011)
Molecular characterization of cannabinoids and free fatty acid receptors in human and rat skeletal muscle
by: Shermado, Fairouz M.
Published: (2014)
by: Shermado, Fairouz M.
Published: (2014)
Fluorescent cannabinoids: Stratagies towards the synthesis of fluorescently labelled CB2 receptor ligands
by: Yates, Andrew Stephen
Published: (2005)
by: Yates, Andrew Stephen
Published: (2005)
The endocannabinoid, anandamide, induces cannabinoid receptor-independent cell death in renal proximal tubule cells
by: Schlosser, Monika, et al.
Published: (2017)
by: Schlosser, Monika, et al.
Published: (2017)
The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation
by: Pieiro, R., et al.
Published: (2011)
by: Pieiro, R., et al.
Published: (2011)
Zerumbone ameliorates neuropathic pain symptoms via
cannabinoid and ppar receptors using in vivo and in
silico models
by: Chia, Jasmine Siew Min, et al.
Published: (2021)
by: Chia, Jasmine Siew Min, et al.
Published: (2021)
Mitragynine (Kratom)-induced cognitive impairments in mice resemble Δ9-THC and morphine effects: reversal by cannabinoid CB1 receptor antagonism
by: Ismail, Nurul Iman, et al.
Published: (2021)
by: Ismail, Nurul Iman, et al.
Published: (2021)
CB1 cannabinoid receptor in brain mesolimbic
system of mitragynine-sensitised albina wastar
rats as a candidate molecular terget in
mitragyna speciosa (KETUM) addiction
by: Mustapha, Muzaimi
Published: (2015)
by: Mustapha, Muzaimi
Published: (2015)
Molecular modelling of the cannabinoid receptors: structure-based design, synthesis and pharmacological evaluation of novel ligands based on the fenofibrate scaffold
by: Loo, Jason S. E.
Published: (2015)
by: Loo, Jason S. E.
Published: (2015)
Patterns of synthetic cannabinoid use in Australia
by: Barratt, Monica, et al.
Published: (2012)
by: Barratt, Monica, et al.
Published: (2012)
Cannabinoid-mediated short-term plasticity in hippocampus
by: Zachariou, Margarita, et al.
Published: (2014)
by: Zachariou, Margarita, et al.
Published: (2014)
Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited
by: Constantinescu, Cris S., et al.
Published: (2018)
by: Constantinescu, Cris S., et al.
Published: (2018)
Synthetic cannabinoids: undesirable alternatives to natural marijuana
by: Palamar, J., et al.
Published: (2016)
by: Palamar, J., et al.
Published: (2016)
Relaxin-family peptide receptors 1 and 2 are fully functional in the bovine
by: Dai, Yanzhenzhi, et al.
Published: (2017)
by: Dai, Yanzhenzhi, et al.
Published: (2017)
The role of cannabinoids in the neurobiology of sensory gating: a firing rate model study
by: Zachariou, Margarita, et al.
Published: (2006)
by: Zachariou, Margarita, et al.
Published: (2006)
Effects of the cannabinoid CB1 agonist ACEA on salicylate ototoxicity, hyperacusis and tinnitus in guinea pigs
by: Berger, Joel I., et al.
Published: (2017)
by: Berger, Joel I., et al.
Published: (2017)
Cannabinoids in experimental stroke: a systematic review and meta-analysis
by: England, Timothy J., et al.
Published: (2015)
by: England, Timothy J., et al.
Published: (2015)
The use of cannabinoids in colitis: a systematic review and meta-analysis
by: Couch, Daniel G., et al.
Published: (2018)
by: Couch, Daniel G., et al.
Published: (2018)
Assessment of GPR18 pairing with putative cannabinoid ligands
by: Abdulrazzaq, Ghayth
Published: (2018)
by: Abdulrazzaq, Ghayth
Published: (2018)
Chromatographic Methods For The Detection Of The Principal Cannabinoid Metabolite In Urine.
by: Vijayan, S., et al.
Published: (1990)
by: Vijayan, S., et al.
Published: (1990)
Synthetic cannabinoid use among high school seniors
by: Palamar, J., et al.
Published: (2017)
by: Palamar, J., et al.
Published: (2017)
Analytical Methods For The Identification And Conformation Of The Principal Cannabinoid Metabolite In Urine.
by: Rajananda, V., et al.
Published: (1985)
by: Rajananda, V., et al.
Published: (1985)
Neurotherapeutic potential of synthetic cannabinoid receptor agonist, WIN55,212-2 on Aluminium chloride and D-galactose- induced cognitive impairments in male Wistar rats
by: Onesimus, Mahdi
Published: (2021)
by: Onesimus, Mahdi
Published: (2021)
Sensory gating and its modulation by cannabinoids: electrophysiological, computational and mathematical analysis
by: Zachariou, Margarita, et al.
Published: (2008)
by: Zachariou, Margarita, et al.
Published: (2008)
Foodomics reveals anti-obesity properties of cannabinoids from hemp oil
by: Ding, Ziwen, et al.
Published: (2023)
by: Ding, Ziwen, et al.
Published: (2023)
The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite
by: Shang, V.C.M., et al.
Published: (2016)
by: Shang, V.C.M., et al.
Published: (2016)
Synthesis and biological evaluation of novel compounds as potential modulators of cannabinoid signalling pathways
by: De Bank, Paul A.
Published: (2001)
by: De Bank, Paul A.
Published: (2001)
Intestinal lymphatic transport of cannabinoids: implications for people with autoimmune diseases and immunocompromised individuals
by: Zgair, Atheer
Published: (2017)
by: Zgair, Atheer
Published: (2017)
Blood-brain barrier disturbances in diabetes-associated dementia: Therapeutic potential for cannabinoids
by: Brook, E., et al.
Published: (2019)
by: Brook, E., et al.
Published: (2019)
Illuminating the life of the adenosine receptors: development and application of subtype-selective fluorescent probes for the study of the human A1 and A2A adenosine receptors in living cells
by: Comeo, Eleonora
Published: (2022)
by: Comeo, Eleonora
Published: (2022)
Similar Items
-
Effect of cannabinoid receptor ligands on microglial cell functions
by: Hassan, Samia
Published: (2013) -
Novel fenofibrate derivatives as cannabinoid receptor ligands
by: Spencer, Sarah Jane
Published: (2011) -
Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis
by: Shi, Y., et al.
Published: (2017) -
Imaging Cannabinoid Receptors: A Brief Collection of Covalent and Fluorescent Probes for CB1 and CB2 Receptors
by: Hamilton, A.J., et al.
Published: (2021) -
Investigating ligand-directed signalling at the cannabinoid receptor 2
by: Hourani, Wafa
Published: (2019)