Importance of Toxin A, Toxin B, and CDT in virulence of an epidemic Clostridium difficile strain

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Importance of Toxin A, Toxin B, and CDT in virulence of an epidemic Clostridium difficile strain

Clostridium difficile infection is the main cause of healthcare-acquired diarrhea in the developed world. In addition to the main virulence factors toxin A and B, epidemic, PCR Ribotype 027 strains, such as R20291, produce a third toxin, CDT. To develop effective medical countermeasures, it is impor...

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Bibliographic Details
Main Authors:	Kuehne, Sarah A., Collery, Mark M., Kelly, Michelle L., Cartman, Stephen T., Cockayne, Alan, Minton, Nigel P.
Format:	Article
Published:	Oxford University Press 2013
Subjects:	Clostridium difficile infection; TcdA; TcdB; pathogenesis; CDT.
Online Access:	https://eprints.nottingham.ac.uk/2815/

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