Folate-mediated macromolecule delivery across the epithelium

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Folate-mediated macromolecule delivery across the epithelium

Folate uses the natural endocytosis pathway via the folate receptor (FR) to enter the cells. Folate conjugation to small or macromolecular therapeutics has hence been exploited for intracellular delivery to, particularly, cancerous cells. This work reports on the expression and functionality of FR i...

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Bibliographic Details
Main Author:	Moradi, Emilia
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2012
Subjects:	Folic acid Folate receptor Drug delivery systems Macromolecular systems Epithelial cells
Online Access:	https://eprints.nottingham.ac.uk/27899/

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